Gene Symbol | IGFBP4 |
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Entrez Gene | 3487 |
Alt Symbol | BP-4, HT29-IGFBP, IBP4, IGFBP-4 |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like growth factor binding protein 4 |
Other Description | IBP-4|IGF-binding protein 4|insulin-like growth factor-binding protein 4 |
Swissprots | Q5U012 B4E351 P22692 Q9UCL6 A0N9W2 |
Accessions | AAA62670 AAR05443 CAA73110 EAW60664 EAW60665 P22692 AK290810 BAF83499 AK304572 BAG65363 BC016041 AAH16041 BT019891 AAV38694 BT019892 AAV38695 BU683435 CN431519 M38177 M62403 AAB06189 NM_001552 NP_001543 |
Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. |
Subcellular Location | Secreted. |
IGFBP4 CRISPR/Cas9 KO Plasmid (h) - sc-402342 from Santa Cruz Biotechnology
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IGFBP4 HDR Plasmid (h) - sc-402342-HDR from Santa Cruz Biotechnology
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IGFBP4 Double Nickase Plasmid (h) - sc-402342-NIC from Santa Cruz Biotechnology
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IGFBP4 Double Nickase Plasmid (h2) - sc-402342-NIC-2 from Santa Cruz Biotechnology
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IGFBP4 CRISPR Activation Plasmid (h) - sc-402342-ACT from Santa Cruz Biotechnology
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IGFBP4 CRISPR Activation Plasmid (h2) - sc-402342-ACT-2 from Santa Cruz Biotechnology
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IGFBP4 Lentiviral Activation Particles (h) - sc-402342-LAC from Santa Cruz Biotechnology
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IGFBP4 Lentiviral Activation Particles (h2) - sc-402342-LAC-2 from Santa Cruz Biotechnology
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IGFBP4 siRNA (h) - sc-39589 from Santa Cruz Biotechnology
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IGFBP4 shRNA Plasmid (h) - sc-39589-SH from Santa Cruz Biotechnology
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IGFBP4 shRNA (h) Lentiviral Particles - sc-39589-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10523 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10523 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12593 from Sigma-Aldrich
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IGFBP4 siRNA (Human) - CRH2358 from Cohesion Biosciences
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IGFBP4 - MBS8209750 from MyBioSource
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shRNA set against Human IGFBP4 (NM_001552.2) - SHH317565 from Creative biogene
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shRNA set against Human IGFBP4(NM_001552.2) - SHL168510 from Creative biogene
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Human IGFBP4 siRNA - orb262860 from Biorbyt
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IGFBP4 shRNA Plasmid (Human) - CHH2358 from Cohesion Biosciences
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IGFBP4 miRNA 3'UTR clone - MiUTR1H-04842 from Creative biogene
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