Gene Symbol | CELE_Y63D3A.4 |
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Entrez Gene | 173276 |
Alt Symbol | - |
Species | C. elegans |
Gene Type | protein-coding |
Description | TDPT-1 |
Other Description | - |
Swissprots | Q9XWG3 |
Accessions | 4GEW_A CAA21707 Q9XWG3 NM_061060 NP_493461 |
Function | DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'- phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Recombinant 5'-tyrosyl-DNA phosphodiesterase(Y63D3A.4) - CSB-YP896444CXY CSB-EP896444CXY CSB-BP896444CXY CSB-MP896444CXY from Cusabio
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5'-tyrosyl-DNA phosphodiesterase (Y63D3A.4), Recombinant Protein - MBS1443960 from MyBioSource
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