Gene Symbol | IL1B1 |
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Entrez Gene | 397122 |
Alt Symbol | IL1B |
Species | Pig |
Gene Type | protein-coding |
Description | interleukin 1, beta 1 |
Other Description | IL-1 beta|interleukin-1 beta|prointerleukin-1 beta |
Swissprots | P26889 |
Accessions | P26889 AK344440 AY577818 AAT00591 M86725 AAA02584 NM_214055 NP_999220 |
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Subcellular Location | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Top Pathways | Cytosolic DNA-sensing pathway, Apoptosis, Inflammatory bowel disease (IBD), Toll-like receptor signaling pathway, Inflammatory mediator regulation of TRP channels |
Anti-IL1 beta antibody (Biotin) - ab193805 from Abcam
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Anti-IL1 beta antibody [DF8] - Azide free - ab194862 from Abcam
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IL-1 beta/IL-1F2 Antibody (77724) - MAB6811 from Novus Biologicals
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IL-1 beta/IL-1F2 Antibody - AF681 from Novus Biologicals
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IL-1 beta/IL-1F2 Antibody [Biotin] - BAF681 from Novus Biologicals
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IL1B Antibody (OASA03711) - OASA03711 from Aviva Systems Biology
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IL-1 beta antibody - orb231830 from Biorbyt
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Interleukin-1 beta / IL-1B antibody - SM2087A from Acris Antibodies
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Mouse Anti-Pig IL-1 beta - DS-MB-01604 from RayBiotech
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Anti-Interleukin 1 Beta (IL1b) - 20-2853 from ARP American Research Products
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IL-1 BETA, Monoclonal Antibody - MBS210240 from MyBioSource
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Anti-Interleukin-1 Beta monoclonal antibody, clone DF8 - CABT-48479MP from Creative Diagnostics
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IL-1 beta Monoclonal Antibody (DF8) - MP425 from Thermo Fisher Scientific
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IL-1 beta Polyclonal Antibody - PP425 from Thermo Fisher Scientific
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IL-1 beta Polyclonal Antibody - ASC0912 from Thermo Fisher Scientific
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IL-1 Beta Antibody | DF8 - MCA2361Z from AbD Serotec
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IL-1 beta / IL1B Antibody, Rabbit PAb, Antigen Affinity Purified - 62003-T16-50 from Sino Biological
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Anti-Pig-Interleukin-1-beta-Antibody-clone-DF8- - ABD11766 from Abgent, a WuXi AppTec company
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IL-1 beta / IL1B Antibody, Rabbit PAb, Antigen Affinity Purified - 62003-T16-200 from Sino Biological
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IL-1 beta Antibody, Rabbit PAb - 62003-RP01-400 from Sino Biological
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