Gene Symbol | Aqp1 |
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Entrez Gene | 11826 |
Alt Symbol | CHIP28 |
Species | Mouse |
Gene Type | protein-coding |
Description | aquaporin 1 |
Other Description | AQP-1|DER2|aquaporin-1|aquaporin-CHIP|delayed early response protein 2|growth factor-induced delayed early response protein|water channel protein for red blood cells and kidney proximal tubule |
Swissprots | Q542P1 Q02013 Q91VY8 |
Accessions | EDK98728 Q02013 AK081886 BAC38360 AK086688 BAC39719 AK128905 AK157333 BAE34051 AK158226 BAE34412 AK158389 BAE34482 AK166280 BAE38677 AK171627 BAE42573 AK172361 BAE42966 BB850287 BC007125 AAH07125 L02914 AAB53928 NM_007472 NP_031498 |
Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. {ECO:0000269|PubMed:12133842}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12133842}; Multi-pass membrane protein {ECO:0000269|PubMed:12133842}. |
Tissue Specificity | Detected in erythrocytes (at protein level). Erythrocytes and renal tubules. {ECO:0000269|PubMed:12133842}. |
Top Pathways | Proximal tubule bicarbonate reclamation, Bile secretion |
AQP1 CRISPR/Cas9 KO Plasmid (m) - sc-419172 from Santa Cruz Biotechnology
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AQP1 HDR Plasmid (m) - sc-419172-HDR from Santa Cruz Biotechnology
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AQP1 Double Nickase Plasmid (m) - sc-419172-NIC from Santa Cruz Biotechnology
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AQP1 Double Nickase Plasmid (m2) - sc-419172-NIC-2 from Santa Cruz Biotechnology
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AQP1 CRISPR Activation Plasmid (m) - sc-419172-ACT from Santa Cruz Biotechnology
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AQP1 CRISPR Activation Plasmid (m2) - sc-419172-ACT-2 from Santa Cruz Biotechnology
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AQP1 Lentiviral Activation Particles (m) - sc-419172-LAC from Santa Cruz Biotechnology
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AQP1 Lentiviral Activation Particles (m2) - sc-419172-LAC-2 from Santa Cruz Biotechnology
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AQP1 siRNA (m) - sc-29712 from Santa Cruz Biotechnology
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AQP1 shRNA Plasmid (m) - sc-29712-SH from Santa Cruz Biotechnology
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AQP1 shRNA (m) Lentiviral Particles - sc-29712-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU037751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26877 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26877 from Sigma-Aldrich
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AQP1 siRNA (Mouse) - CRM0229 from Cohesion Biosciences
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AQP1 - MBS8203624 from MyBioSource
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shRNA set against Mouse AQP1 (NM_007472.2) - SHH238802 from Creative biogene
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shRNA set against Mouse Aqp1(NM_007472.2) - SHG066581 from Creative biogene
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AQP1 CRISPR/Cas9 KO Plasmid (m2) - sc-419172-KO-2 from Santa Cruz Biotechnology
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AQP1 HDR Plasmid (m2) - sc-419172-HDR-2 from Santa Cruz Biotechnology
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Mouse Aquaporin 1 siRNA - orb279705 from Biorbyt
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AQP1 shRNA Plasmid (Mouse) - CHM0229 from Cohesion Biosciences
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AQP1 miRNA 3'UTR clone - MiUTR1M-01602 from Creative biogene
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