Gene Symbol | CRYM |
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Entrez Gene | 1428 |
Alt Symbol | DFNA40, THBP |
Species | Human |
Gene Type | protein-coding |
Description | crystallin, mu |
Other Description | NADP-regulated thyroid-hormone binding protein|ketimine reductase mu-crystallin|mu-crystallin homolog|thiomorpholine-carboxylate dehydrogenase |
Swissprots | D5MNX0 Q5HYB7 Q14894 |
Accessions | AAB67600 AAB94938 EAW66862 EAW66863 Q14894 AK290852 BAF83541 AK310424 BC008398 BC018061 AAH18061 BG033512 BI860684 BX648477 CAI46030 DQ892377 ABM83303 DQ895591 ABM86517 L02950 AAC16914 U85772 AAB81564 XM_011545740 XP_011544042 NM_001888 NP_001879 NM_001014444 |
Function | Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. {ECO:0000269|PubMed:21332720}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed in neural tissue, muscle and kidney. |
μ-crystallin (F-11) - sc-376687 from Santa Cruz Biotechnology
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μ-crystallin (E-8) - sc-393048 from Santa Cruz Biotechnology
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μ-crystallin (H-293) - sc-366780 from Santa Cruz Biotechnology
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μ-crystallin (L-20) - sc-22424 from Santa Cruz Biotechnology
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μ-crystallin (N-21) - sc-22423 from Santa Cruz Biotechnology
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Anti-mu Crystallin antibody - ab54669 from Abcam
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Anti-mu Crystallin antibody - ab104328 from Abcam
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Anti-mu Crystallin antibody [1B5] - ab118986 from Abcam
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Anti-CRYM Antibody (aa179-228) - LS-C111353 from LifeSpan Bioscience
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Anti-CRYM Antibody - LS-C310002 from LifeSpan Bioscience
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Anti-CRYM Antibody - LS-C310003 from LifeSpan Bioscience
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Anti-CRYM Antibody (aa154-183) - LS-C320621 from LifeSpan Bioscience
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Anti-CRYM Antibody (aa215-315, Azide-free) - LS-C327133 from LifeSpan Bioscience
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Anti-CRYM Antibody (aa71-120) - LS-C111352 from LifeSpan Bioscience
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Anti-CRYM Antibody (aa154-183) - LS-C157663 from LifeSpan Bioscience
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Anti-CRYM Antibody (clone 1B5) - LS-C115420 from LifeSpan Bioscience
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Anti-CRYM Antibody (clone 6B3) IHC-plus™ - LS-B4306 from LifeSpan Bioscience
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Anti-CRYM Antibody (clone 1G7) IHC-plus™ - LS-B9468 from LifeSpan Bioscience
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mu Crystallin Antibody (1G7) - NBP2-02829 from Novus Biologicals
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mu Crystallin Antibody (6B3) - H00001428-M03 from Novus Biologicals
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mu Crystallin Antibody - NBP1-85241 from Novus Biologicals
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mu Crystallin Antibody (1C6) - H00001428-M09 from Novus Biologicals
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mu Crystallin Antibody - H00001428-D01P from Novus Biologicals
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mu Crystallin Antibody - H00001428-B01 from Novus Biologicals
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mu Crystallin Antibody - H00001428-A01 from Novus Biologicals
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