| Gene Symbol |
STK38
|
| Entrez Gene |
11329
|
| Alt Symbol |
NDR, NDR1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serine/threonine kinase 38
|
| Other Description |
NDR1 protein kinase|Ndr Ser/Thr kinase-like protein|nuclear Dbf2-related kinase 1|serine/threonine-protein kinase 38
|
| Swissprots |
Q503A1 Q15208
|
| Accessions |
CAG44584 EAX03894 EAX03895 EAX03896 Q15208 AF034187 AAD50529 AF034188 AAD50530 AK095337 AK312559 BAG35456 BC012085 AAH12085 BC095413 AAH95413 CB852856 DA459946 EU832099 ACE87449 EU832192 ACE86762 Z35102 CAA84485 XM_005248839 XP_005248896 XM_006714988 XP_006715051 XM_006714989 XP_006715052 XM_011514277 XP_011512579 XM_011514278 XP_011512580 XR_926047 NM_001305102 NP_001292031 NM_007271 NP_009202
|
| Function |
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2. {ECO:0000269|PubMed:12493777, ECO:0000269|PubMed:15197186, ECO:0000269|PubMed:17906693, ECO:0000269|PubMed:7761441}.
|
| Subcellular Location |
Nucleus. Cytoplasm.
|
| Tissue Specificity |
Ubiquitously expressed with highest levels observed in peripheral blood leukocytes. {ECO:0000269|PubMed:15197186, ECO:0000269|PubMed:7761441}.
|