| Gene Symbol |
ST13
|
| Entrez Gene |
6767
|
| Alt Symbol |
AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
|
| Other Description |
Hsp70-interacting protein|aging-associated protein 2|heat shock 70kD protein binding protein|hsc70-interacting protein|progesterone receptor-associated p48 protein|putative tumor suppressor ST13|renal carcinoma antigen NY-REN-33|suppression of tumorigenicity 13 protein
|
| Swissprots |
O14999 P50502 Q2TU77
|
| Accessions |
EAW60394 EAW60395 EAW60396 P50502 AF116650 AAF71070 AK130770 AK303530 BAG64558 AK312399 AK316155 BAH14526 AY513286 AAT08039 AY826824 AAX18644 AY826825 AAX18645 BC015317 AAH15317 BC052982 AAH52982 BC071629 AAH71629 BC101206 BC101207 BC101208 BC107148 AAI07149 BC121107 AAI21108 BC121108 AAI21109 BC139724 AAI39725 BG706239 BM679025 CR456586 CAG30472 CU013186 CAK54617 CU013474 CAK54916 U17714 AAC97526 U28918 AAB38382 NM_001278589 NP_001265518 NM_003932 NP_003923
|
| Function |
One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|