GDF6

Gene Symbol GDF6
Entrez Gene 392255
Alt Symbol BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1
Species Human
Gene Type protein-coding
Description growth differentiation factor 6
Other Description GDF-6|Klip-Feil malformation|Klippel-Feil malformation|Klippel-Feil syndrome|bone morphogenetic protein 13|growth/differentiation factor 16|growth/differentiation factor 6
Swissprots Q6PI58 Q6KF10
Accessions AGF34263 AGF34264 EAW91747 Q6KF10 AJ537424 CAD60934 BC043222 AAH43222 BC127947 AAI27948 BC127948 AAI27949 BC156445 AAI56446 XM_011517030 XP_011515332 NM_001001557 NP_001001557
Function Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. May signal through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A. {ECO:0000269|PubMed:23307924}.
Subcellular Location Secreted {ECO:0000269|PubMed:23307924}.
Top Pathways TGF-beta signaling pathway, Hippo signaling pathway

GDF-6 CRISPR/Cas9 KO Plasmid (h) - sc-406607 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 HDR Plasmid (h) - sc-406607-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 Double Nickase Plasmid (h) - sc-406607-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 Double Nickase Plasmid (h2) - sc-406607-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 CRISPR Activation Plasmid (h) - sc-406607-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 CRISPR Activation Plasmid (h2) - sc-406607-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 Lentiviral Activation Particles (h) - sc-406607-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 Lentiviral Activation Particles (h2) - sc-406607-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GDF-6 siRNA (h) - sc-39770 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GDF-6 shRNA Plasmid (h) - sc-39770-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GDF-6 shRNA (h) Lentiviral Particles - sc-39770-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9216 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9216 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11095 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11095

GDF6 siRNA (Human) - CRJ8037 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GDF6 - MBS8223073 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GDF6 (NM_001001557.2) - SHH300322 from Creative biogene

Category siRNA
Species Reactivities Human

GDF6 shRNA Plasmid (Human) - CHJ8037 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GDF6 miRNA 3'UTR clone - MiUTR4H-TG03763 from Creative biogene

Species Reactivities Human
Search more