Gene Symbol | SESTD1 |
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Entrez Gene | 91404 |
Alt Symbol | SOLO |
Species | Human |
Gene Type | protein-coding |
Description | SEC14 and spectrin domains 1 |
Other Description | SEC14 domain and spectrin repeat-containing protein 1|huntingtin-interacting protein-like protein|protein Solo |
Swissprots | Q53R38 Q96LQ2 Q53SP3 Q8N6M1 Q5GM69 Q86VW0 |
Accessions | AAY24093 AAY24323 CAD10189 EAX11010 Q86VW0 AK056075 AK057944 BAB71618 AK096232 BAG53235 AL122046 CAB59182 AY209190 AAP47744 BC029744 AAH29744 BC047578 AAH47578 BC053862 AAH53862 BC061918 EU832125 ACE87475 EU832219 ACE86789 XM_011512139 XP_011510441 XM_011512140 XP_011510442 XM_011512141 XP_011510443 XR_923061 NM_178123 NP_835224 |
Function | May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1. {ECO:0000269|PubMed:20164195}. |
Tissue Specificity | Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature. {ECO:0000269|PubMed:20164195}. |
Human Solo full length protein - ab164851 from Abcam
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SOLO / SESTD1 Antibody Blocking Peptide - LS-E30978 from LifeSpan Bioscience
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Recombinant Human Solo Protein - H00091404-P01 from Novus Biologicals
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Solo Peptide - NBP1-76279PEP from Novus Biologicals
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SESTD1-Antibody-N-term-Blocking-Peptide - BP14214a from Abgent, a WuXi AppTec company
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SESTD1 Peptide - GTX85164-PEP from GeneTex
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SESTD1 / SOLO - H00091404-P01-10 from Acris Antibodies
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SESTD1 / SOLO - H00091404-P01-25 from Acris Antibodies
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SESTD1 / SOLO control peptide - AP26250CP-N from Acris Antibodies
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SESTD1 Peptide - 5877P from ProSci
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SESTD1 fusion protein - Ag21016 from Proteintech Group
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Recombinant Human SEC14 domain and spectrin repeat-containing protein 1(SESTD1) - CSB-YP801241HU CSB-EP801241HU CSB-BP801241HU CSB-MP801241HU from Cusabio
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SESTD1 / SOLO - TP307976 from Acris Antibodies
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SEC14 domain and spectrin repeat-containing protein 1 (SESTD1), Recombinant Protein - MBS1358684 from MyBioSource
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