| Gene Symbol |
HLX
|
| Entrez Gene |
3142
|
| Alt Symbol |
HB24, HLX1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
H2.0-like homeobox
|
| Other Description |
H2.0-like homeo box 1|H2.0-like homeo box-1|H2.0-like homeobox 1|H2.0-like homeobox protein|homeobox protein HB24|homeobox protein HLX1
|
| Swissprots |
Q9NZ75 Q15988 B2R8A8 Q14774 Q59HE7
|
| Accessions |
AAC51346 AAD13883 AAD13884 AAD13885 AAF65541 EAW93288 EAW93289 Q14774 AB208812 BAD92049 AK056326 AK127923 BAG54598 AK313298 BAG36105 BC007294 AAH07294 BC033808 AAH33808 DA951303 DQ893305 ABM84231 DQ896761 ABM87760 M60721 NM_021958 NP_068777
|
| Function |
Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
|
| Tissue Specificity |
Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
|