Gene Symbol | LRRC4B |
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Entrez Gene | 94030 |
Alt Symbol | HSM, LRIG4 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 4B |
Other Description | NGL-3|leucine-rich repeat-containing protein 4B|leucine-rich repeats and immunoglobulin-like domains 4|netrin-G3 ligand |
Swissprots | Q3ZCQ4 Q9NT99 Q58F20 |
Accessions | CAD29039 CAD61785 CAI96013 EAW71884 EAW71885 EAW71886 Q9NT99 AL137451 CAB70743 BC019687 AAH19687 BC032460 AAH32460 BC056207 AAH56207 BC131897 AAI31898 BC156079 AAI56080 BC172459 AAI72459 XM_005259429 XP_005259486 XM_006723506 XP_006723569 XM_011527520 XP_011525822 NM_001080457 NP_001073926 |
Function | Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass membrane protein. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}. |
Top Pathways | Cell adhesion molecules (CAMs) |
LRRC4B CRISPR/Cas9 KO Plasmid (h) - sc-410245 from Santa Cruz Biotechnology
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LRRC4B HDR Plasmid (h) - sc-410245-HDR from Santa Cruz Biotechnology
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LRRC4B Double Nickase Plasmid (h) - sc-410245-NIC from Santa Cruz Biotechnology
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LRRC4B Double Nickase Plasmid (h2) - sc-410245-NIC-2 from Santa Cruz Biotechnology
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LRRC4B CRISPR Activation Plasmid (h) - sc-410245-ACT from Santa Cruz Biotechnology
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LRRC4B CRISPR Activation Plasmid (h2) - sc-410245-ACT-2 from Santa Cruz Biotechnology
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LRRC4B Lentiviral Activation Particles (h) - sc-410245-LAC from Santa Cruz Biotechnology
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LRRC4B Lentiviral Activation Particles (h2) - sc-410245-LAC-2 from Santa Cruz Biotechnology
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LRRC4B siRNA (h) - sc-97558 from Santa Cruz Biotechnology
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LRRC4B shRNA Plasmid (h) - sc-97558-SH from Santa Cruz Biotechnology
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LRRC4B shRNA (h) Lentiviral Particles - sc-97558-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12748 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12748 from Sigma-Aldrich
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LRRC4B siRNA (Human) - CRJ4239 from Cohesion Biosciences
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shRNA set against Human Lrrc4b (NM_001080457.1) - SHH334635 from Creative biogene
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shRNA set against Human LRRC4B(NM_001080457.1) - SHH163235 from Creative biogene
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Human LRRC4B siRNA - orb274740 from Biorbyt
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LRRC4B shRNA Plasmid (Human) - CHJ4239 from Cohesion Biosciences
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LRRC4B miRNA 3'UTR clone - MiUTR1H-05923 from Creative biogene
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