| Gene Symbol |
NRAS
|
| Entrez Gene |
4893
|
| Alt Symbol |
ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuroblastoma RAS viral (v-ras) oncogene homolog
|
| Other Description |
GTPase NRas|N-ras protein part 4|transforming protein N-Ras|v-ras neuroblastoma RAS viral oncogene homolog
|
| Swissprots |
Q14971 Q15104 Q15282 P01111
|
| Accessions |
AAA36548 AAA36556 AAA60255 AAB29639 AAQ94397 ABY87546 CAA25269 CAA25270 CAA25271 CAA25272 CAA29078 CAA29079 CAA30320 CAA37384 CBV35642 CDL93481 EAW56608 EAW56609 EAW56610 EAW56611 P01111 AF493919 AAM12633 AW021410 AY941100 AY941101 BC005219 AAH05219 BC013214 BT019734 AAV38539 BT019735 AAV38540 DA007844 X02751 CAA26529 NM_002524 NP_002515
|
| Function |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15705808}; Lipid-anchor {ECO:0000269|PubMed:15705808}; Cytoplasmic side {ECO:0000269|PubMed:15705808}. Golgi apparatus membrane {ECO:0000269|PubMed:15705808}; Lipid-anchor {ECO:0000269|PubMed:15705808}. Note=Shuttles between the plasma membrane and the Golgi apparatus.
|
| Top Pathways |
Sphingolipid signaling pathway, Axon guidance, PI3K-Akt signaling pathway, Rap1 signaling pathway, Choline metabolism in cancer
|
![Western Blot: NRAS Overexpression Lysate (Adult Normal) [NBL1-13785] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NRAS.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4233_NRAS%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13785-img0002.jpg)