| Gene Symbol |
ADGRA2
|
| Entrez Gene |
25960
|
| Alt Symbol |
GPR124, TEM5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adhesion G protein-coupled receptor A2
|
| Other Description |
G protein-coupled receptor 124|G-protein coupled receptor 124|tumor endothelial marker 5
|
| Swissprots |
Q9P1Z7 Q96PE1 Q8TEM3 A6H8W3 Q96KB2 D3DSW4 Q8N3R1 Q9UFY4
|
| Accessions |
EAW63354 EAW63355 EAW63356 EAW63357 EAW63358 EAW63359 Q96PE1 AB040964 BAA96055 AF378755 AAL11992 AI346793 AK027296 BAB55022 AK074099 BAB84925 AL110244 CAB53694 AL137610 AL832524 CAD38629 AL832959 CAH56283 AY090637 AAM09084 AY181242 AAO27354 BC146774 AAI46775 DA569569 XM_005273471 XP_005273528 XM_011544481 XP_011542783 XM_011544482 XP_011542784 XM_011544483 XP_011542785 NM_032777 NP_116166
|
| Function |
Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. {ECO:0000269|PubMed:15021905}.
|