Gene Symbol | HEXB |
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Entrez Gene | 3074 |
Alt Symbol | ENC-1AS, HEL-248 |
Species | Human |
Gene Type | protein-coding |
Description | hexosaminidase B (beta polypeptide) |
Other Description | HCC-7|N-acetyl-beta-glucosaminidase subunit beta|beta-N-acetylhexosaminidase subunit beta|beta-hexosaminidase subunit beta|cervical cancer proto-oncogene 7 protein|epididymis luminal protein 248|hexosaminidase subunit B |
Swissprots | P07686 |
Accessions | AAA52645 EAW95741 EAW95742 P07686 AF378118 AAM46114 AK122992 AK130002 AK130375 AY643499 AAV48875 BC017378 AAH17378 BE907813 BT009919 AAP88921 D10518 D10519 D10520 FJ224336 ACI46028 JF432353 ADZ15570 M13519 AAA51828 M19735 AAA68620 M34906 AAA51829 NM_000521 NP_000512 NM_001292004 NP_001278933 |
Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation |
HEXB CRISPR/Cas9 KO Plasmid (h) - sc-404765 from Santa Cruz Biotechnology
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HEXB HDR Plasmid (h) - sc-404765-HDR from Santa Cruz Biotechnology
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HEXB Double Nickase Plasmid (h) - sc-404765-NIC from Santa Cruz Biotechnology
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HEXB Double Nickase Plasmid (h2) - sc-404765-NIC-2 from Santa Cruz Biotechnology
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HEXB CRISPR Activation Plasmid (h) - sc-404765-ACT from Santa Cruz Biotechnology
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HEXB CRISPR Activation Plasmid (h2) - sc-404765-ACT-2 from Santa Cruz Biotechnology
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HEXB Lentiviral Activation Particles (h) - sc-404765-LAC from Santa Cruz Biotechnology
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HEXB Lentiviral Activation Particles (h2) - sc-404765-LAC-2 from Santa Cruz Biotechnology
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HEXB siRNA (h) - sc-60785 from Santa Cruz Biotechnology
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HEXB shRNA Plasmid (h) - sc-60785-SH from Santa Cruz Biotechnology
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HEXB shRNA (h) Lentiviral Particles - sc-60785-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU044341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10001 from Sigma-Aldrich
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HEXB siRNA (Human) - CRH2094 from Cohesion Biosciences
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HEXB - MBS8237162 from MyBioSource
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shRNA set against Human HEXB (NM_000521.3) - SHH311777 from Creative biogene
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HEXB shRNA Plasmid (Human) - CHH2094 from Cohesion Biosciences
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HEXB miRNA 3'UTR clone - MiUTR3H-08789 from Creative biogene
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