Gene Symbol | MC2R |
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Entrez Gene | 4158 |
Alt Symbol | ACTHR |
Species | Human |
Gene Type | protein-coding |
Description | melanocortin 2 receptor (adrenocorticotropic hormone) |
Other Description | ACTH receptor|MC2 receptor|adrenocorticotropic hormone receptor|adrenocorticotropin receptor|corticotropin receptor |
Swissprots | Q504X6 Q01718 Q3MI45 A8K016 |
Accessions | AAD14989 AAO67714 BAC06130 CAA46587 EAX01503 Q01718 AK289381 BAF82070 AK315319 BAG37722 BC069074 AAH69074 BC094710 AAH94710 BC104169 AAI04170 BC104170 AAI04171 BP196054 Y10259 NM_000529 NP_000520 NM_001291911 NP_001278840 |
Function | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). {ECO:0000269|PubMed:19329486, ECO:0000269|PubMed:20371771}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
Human MC2 receptor full length protein - ab152516 from Abcam
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MC2R / ACTHR / ACTH Receptor Antibody Blocking Peptide - LS-E7880 from LifeSpan Bioscience
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MC2R / ACTHR / ACTH Receptor Antibody Blocking Peptide - LS-E23220 from LifeSpan Bioscience
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MC2R / ACTHR / ACTH Receptor Antibody Blocking Peptide - LS-E26587 from LifeSpan Bioscience
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Recombinant Human Melanocortin-2 R/MC2R Protein - H00004158-P01 from Novus Biologicals
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MC2R-Antibody-C-term-Blocking-peptide - BP5540b from Abgent, a WuXi AppTec company
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MC2 Receptor blocking peptide - GTX88891-PEP from GeneTex
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MC2 Peptide - AC21-1423-P from Abcore
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MC2-R - H00004158-G01 from Acris Antibodies
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MC2-R - H00004158-P01 from Acris Antibodies
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MC2R Peptide - 45-870P from ProSci
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Recombinant Adrenocorticotropic Hormone Receptor (ACTHR) - RPD048Ra01 from Uscn Life Science Inc.
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MC2-R (K289) Peptide - BS2783P from Bioworld Technology
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Recombinant Human Melanocortin-2 R/MC2R Protein - H00004158-G01 from Novus Biologicals
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MC2-R - TP310483 from Acris Antibodies
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MC2R/ACTHR, Peptide - MBS425677 from MyBioSource
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MC2R Peptide, Human - M34GP09295H from Creative Peptides
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GPS1573 Peptide - 350595 from ABBIOTEC
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MC2R Immunizing peptide - orb50387 from Biorbyt
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