| Gene Symbol |
CKLF
|
| Entrez Gene |
51192
|
| Alt Symbol |
C32, CKLF1, CKLF2, CKLF3, CKLF4, HSPC224, UCK-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine-like factor
|
| Other Description |
chemokine-like factor 1|chemokine-like factor 2|chemokine-like factor 3|chemokine-like factor 4|transmembrane proteolipid
|
| Swissprots |
Q9UHM7 C9JE38 Q9UBR5 Q9UI41 Q9UHN8
|
| Accessions |
AAT70694 CAT04648 EAW83019 EAW83020 EAW83021 EAW83022 Q9UBR5 AA234074 AF057306 AAF21255 AF096895 AAF06722 AF135380 AAF19599 AF135381 AAF19600 AF145216 AAF19350 AF151058 AAF36144 AK290307 BAF82996 AK301240 BAG62809 AY358999 AAQ89358 BC004380 AAH04380 BC091478 AAH91478 BU189908 DA113473 DA804889 DQ893388 ABM84314 DQ896708 ABM87707 NM_001040138 NP_001035228 NM_016326 NP_057410 NM_016951 NP_058647 NM_181640 NP_857591 NM_181641 NP_857592 NM_001040139
|
| Function |
May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10. {ECO:0000269|PubMed:11415443}.
|
| Subcellular Location |
Isoform 4: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver. {ECO:0000269|PubMed:11415443}.
|