IL12A

Gene Symbol IL12A
Entrez Gene 3592
Alt Symbol CLMF, IL-12A, NFSK, NKSF1, P35
Species Human
Gene Type protein-coding
Description interleukin 12A
Other Description CLMF p35|IL-12, subunit p35|IL35 subunit|NF cell stimulatory factor chain 1|NK cell stimulatory factor chain 1|cytotoxic lymphocyte maturation factor 1, p35|cytotoxic lymphocyte maturation factor 35 kDa subunit|interleukin 12, p35|interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)|interleukin-12 alpha chain|interleukin-12 subunit alpha
Swissprots P29459 Q96QZ1
Accessions AAC05211 AAC05212 AAK84425 CAM82732 CBX32667 CCA63969 EAW78656 EAW78657 EAW78658 P29459 AF101062 AAD16432 AF180562 AAD56385 AW472810 BC035571 BC104982 AAI04983 BC104984 AAI04985 BG702253 M65271 AAA35694 M65291 AAA59937 NM_000882 NP_000873
Function Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Subcellular Location Secreted.
Top Pathways Herpes simplex infection, Malaria, Tuberculosis, Influenza A, Measles

IL-12 (500-M12) - sc-65354 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-12 (JJ07) - sc-74147 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-12 p70 (14L7) - sc-74150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-12 p70 (QS-12p70) - sc-57257 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-12A p35 (H-197) - sc-7925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-12A p35 (H-197): sc-7925. Western blot analysis of IL-12A p35 expression in MOLT-4 whole cell lysate.

IL-12A p35 (C-19) - sc-1280 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-12A p35/p70 (B-T21) - sc-65323 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-IL12 antibody - ab9992 from Abcam

Prices $379.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
IHC image of ab9992 staining in human astrocytoma formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab9992, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-IL12 antibody - ab124635 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab124635, at 3.75µg/ml, staining IL12 in formalin-fixed, paraffin-embedded Human intestine (paneth cells) tissue by Immunohistochemistry.

Anti-IL12 antibody - ab119477 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL12 antibody (ab119477) at 1 µg/mlLane 1 : Recombinant Human IL12 protein at 0.01 µgLane 2 : Recombinant Human IL12 protein at 0.005 µgLane 3 : Recombinant Human IL12 protein at 0.0025 µg

Anti-IL12 antibody [1-1A4] - ab11446 from Abcam

Prices $370.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 1-1A4

Anti-IL12 antibody (Biotin) - ab83448 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-IL12 antibody [C8.1] - ab25100 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone C8.1

Anti-IL12 antibody [HP-40] (Phycoerythrin) - ab95528 from Abcam

Prices $376.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone HP-40
Intracellular staining of unstimulated (left) or IFN?, LPS, and Monensin stimulated (right) normal Human peripheral blood cells with Anti-Human CD14 FITC and ab95528. Cells in the monocyte gate were used for analysis.

Anti-IL12 antibody [MM0362-7M58] - ab89889 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0362-7M58

Anti-IL12 p35 + IL12 p70 antibody [B-T21] - ab27400 from Abcam

Prices $370.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone B-T21

Anti-IL12 p35 + IL12 p70 antibody [B-T21] (FITC) - ab27401 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-T21
Overlay histogram showing peripheral blood lymphocytes cells stained with ab27401 (red line). The cells were fixed with 4% paraformaldehydel (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab27401, 0.5µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 (0.5µg/1x106 cells ). Acquisition of >5,000 events was performed.

Anti-IL12 p35 antibody - ab157765 from Abcam

Host Sheep
Clonality Polyclonal

Anti-IL12 p40 + IL12 p70 antibody [B-P24] - ab27364 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-P24

Anti-IL12 p40 + IL12 p70 antibody [B-P24] (FITC) - ab27376 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-P24
Overlay histogram showing peripheral blood lymphocytes cells stained with ab27376 (red line). The cells were fixed with 4% paraformaldehydel (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab27376, 0.5µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 (0.5µg/1x106 cells ). Acquisition of >5,000 events was performed.

Anti-IL12 p40 + IL12 p70 antibody [B-P40] - ab27379 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-P40

Anti-IL12 p70 antibody - ab25105 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL12 p70 antibody (Biotin) - ab25106 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL12 p70 antibody [QS-12p70] - ab25036 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone QS-12p70

Anti-IL12A antibody - ab135455 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL12A antibody (ab135455) at 1/500 dilution + HeLa cell extract at 30 µg
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