Gene Symbol | MTTP |
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Entrez Gene | 4547 |
Alt Symbol | ABL, MTP |
Species | Human |
Gene Type | protein-coding |
Description | microsomal triglyceride transfer protein |
Other Description | microsomal triglyceride transfer protein (large polypeptide, 88kDa)|microsomal triglyceride transfer protein large subunit |
Swissprots | P55157 Q6P5T3 A8K428 Q08AM4 |
Accessions | AAD14146 AAD14961 CAA58142 EAX06106 P55157 AA609331 AI623321 AK225328 AK290793 BAF83482 AK302602 BAH13759 BC062696 AAH62696 BC125110 AAI25111 BC125111 AAI25112 BE047932 CB162574 DB083001 DB458800 X59657 CAA42200 X75500 CAA53217 X91148 CAA62585 NM_000253 NP_000244 NM_001300785 NP_001287714 |
Function | Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B. |
Subcellular Location | Endoplasmic reticulum. |
Tissue Specificity | Liver and small intestine. Also found in ovary, testis and kidney. {ECO:0000269|PubMed:7961826}. |
Top Pathways | Fat digestion and absorption |
MTP CRISPR/Cas9 KO Plasmid (h) - sc-401884 from Santa Cruz Biotechnology
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MTP HDR Plasmid (h) - sc-401884-HDR from Santa Cruz Biotechnology
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MTP Double Nickase Plasmid (h) - sc-401884-NIC from Santa Cruz Biotechnology
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MTP Double Nickase Plasmid (h2) - sc-401884-NIC-2 from Santa Cruz Biotechnology
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MTP CRISPR Activation Plasmid (h) - sc-401884-ACT from Santa Cruz Biotechnology
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MTP CRISPR Activation Plasmid (h2) - sc-401884-ACT-2 from Santa Cruz Biotechnology
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MTP Lentiviral Activation Particles (h) - sc-401884-LAC from Santa Cruz Biotechnology
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MTP Lentiviral Activation Particles (h2) - sc-401884-LAC-2 from Santa Cruz Biotechnology
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MTP siRNA (h) - sc-45275 from Santa Cruz Biotechnology
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MTP shRNA Plasmid (h) - sc-45275-SH from Santa Cruz Biotechnology
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MTP shRNA (h) Lentiviral Particles - sc-45275-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU086741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1667 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1667 from Sigma-Aldrich
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MTTP siRNA (Human) - CRH3015 from Cohesion Biosciences
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shRNA set against Human MTTP (NM_000253.2) - SHH346752 from Creative biogene
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Human MTTP siRNA - orb263517 from Biorbyt
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MTTP shRNA Plasmid (Human) - CHH3015 from Cohesion Biosciences
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MTTP miRNA 3'UTR clone - MiUTR1H-06525 from Creative biogene
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