Gene Symbol |
MTTP
|
Entrez Gene |
4547
|
Alt Symbol |
ABL, MTP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
microsomal triglyceride transfer protein
|
Other Description |
microsomal triglyceride transfer protein (large polypeptide, 88kDa)|microsomal triglyceride transfer protein large subunit
|
Swissprots |
P55157 Q6P5T3 A8K428 Q08AM4
|
Accessions |
AAD14146 AAD14961 CAA58142 EAX06106 P55157 AA609331 AI623321 AK225328 AK290793 BAF83482 AK302602 BAH13759 BC062696 AAH62696 BC125110 AAI25111 BC125111 AAI25112 BE047932 CB162574 DB083001 DB458800 X59657 CAA42200 X75500 CAA53217 X91148 CAA62585 NM_000253 NP_000244 NM_001300785 NP_001287714
|
Function |
Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.
|
Subcellular Location |
Endoplasmic reticulum.
|
Tissue Specificity |
Liver and small intestine. Also found in ovary, testis and kidney. {ECO:0000269|PubMed:7961826}.
|
Top Pathways |
Fat digestion and absorption
|