Gene Symbol | AMACR |
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Entrez Gene | 23600 |
Alt Symbol | AMACRD, CBAS4, RACE, RM |
Species | Human |
Gene Type | protein-coding |
Description | alpha-methylacyl-CoA racemase |
Other Description | 2-methylacyl-CoA racemase |
Swissprots | Q9Y3Q1 Q96GH1 Q3KT79 A5YM47 O43673 B8Y916 F8W9N1 B8Y918 Q9UHK6 |
Accessions | EAX10815 EAX10816 EAX10817 EAX10818 Q9UHK6 AA969512 AF047020 AAD10205 AF158378 AAF22610 AJ130733 CAB44062 AK000912 BAG50838 AK022765 BAG51110 AK222831 BAD96551 AK225749 AK292988 BAF85677 AL545355 AL571115 AM392625 CAL37503 AY330488 AAQ67234 AY330489 AAQ94259 AY935981 AAY16192 BC009471 AAH09471 BG708726 BI550368 BQ941482 BT007193 AAP35857 DA156454 EF560721 ABQ59031 FJ498906 ACL67853 FJ498907 ACL67854 FJ498908 ACL67855 NM_001167595 NP_001161067 NM_014324 NP_055139 NM_203382 NP_976316 NM_001167596 NM_001167597 NM_001167598 |
Function | Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:11060344}. Mitochondrion {ECO:0000269|PubMed:11060344}. |
Top Pathways | Primary bile acid biosynthesis, Peroxisome |
P504S CRISPR/Cas9 KO Plasmid (h) - sc-403603 from Santa Cruz Biotechnology
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P504S HDR Plasmid (h) - sc-403603-HDR from Santa Cruz Biotechnology
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P504S Double Nickase Plasmid (h) - sc-403603-NIC from Santa Cruz Biotechnology
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P504S Double Nickase Plasmid (h2) - sc-403603-NIC-2 from Santa Cruz Biotechnology
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P504S CRISPR Activation Plasmid (h) - sc-403603-ACT from Santa Cruz Biotechnology
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P504S CRISPR Activation Plasmid (h2) - sc-403603-ACT-2 from Santa Cruz Biotechnology
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P504S Lentiviral Activation Particles (h) - sc-403603-LAC from Santa Cruz Biotechnology
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P504S Lentiviral Activation Particles (h2) - sc-403603-LAC-2 from Santa Cruz Biotechnology
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P504S siRNA (h) - sc-92063 from Santa Cruz Biotechnology
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P504S shRNA Plasmid (h) - sc-92063-SH from Santa Cruz Biotechnology
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P504S shRNA (h) Lentiviral Particles - sc-92063-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3101 from Sigma-Aldrich
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AMACR siRNA (Human) - CRH8389 from Cohesion Biosciences
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alpha-Methylacyl-CoA Racemase/AMACR RNAi - H00023600-R01 from Novus Biologicals
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alpha-Methylacyl-CoA Racemase/AMACR RNAi - H00023600-R02 from Novus Biologicals
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AMACR - MBS8203951 from MyBioSource
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shRNA set against Human AMACR (NM_014324.5) - SHH235622 from Creative biogene
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AMACR shRNA Plasmid (Human) - CHH8389 from Cohesion Biosciences
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AMACR miRNA 3'UTR clone - MiUTR4H-TG00291 from Creative biogene
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