Gene Symbol | SMTNL1 |
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Entrez Gene | 219537 |
Alt Symbol | CHASM |
Species | Human |
Gene Type | protein-coding |
Description | smoothelin-like 1 |
Other Description | calponin homology-associated smooth muscle protein|smoothelin-like protein 1 |
Swissprots | A8MU46 |
Accessions | A8MU46 BC172381 AAI72381 XM_005273819 XP_005273876 NM_001105565 NP_001099035 |
Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, myofibril {ECO:0000269|PubMed:18310078}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in striated muscles, specifically in type 2a fibers (at protein level). {ECO:0000269|PubMed:18310078, ECO:0000269|PubMed:20634291}. |
SMTNL1 Antibody Blocking Peptide - LS-E1015 from LifeSpan Bioscience
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SMTNL1-Antibody-Center-Blocking-peptide - BP11480c from Abgent, a WuXi AppTec company
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Recombinant Human SMTNL1 - SMTNL1-1197H from Creative Biomart
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Recombinant Human Smoothelin-like protein 1(SMTNL1) - CSB-YP021856HU CSB-EP021856HU CSB-BP021856HU CSB-MP021856HU from Cusabio
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Smoothelin-like 1 (SMTNL1) - TP325882 from Acris Antibodies
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SMTNL1 Protein - NBP1-90630PEP from Novus Biologicals
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SMTNL1 Peptide, Human - M34GP14779H from Creative Peptides
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Smoothelin-like protein 1 (SMTNL1), Recombinant Protein - MBS1188853 from MyBioSource
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