ADSL

Gene Symbol ADSL
Entrez Gene 158
Alt Symbol AMPS, ASASE, ASL
Species Human
Gene Type protein-coding
Description adenylosuccinate lyase
Other Description adenylosuccinase
Swissprots Q5TI34 B0QY76 P30566 O75495
Accessions AAC83935 EAW60375 EAW60376 EAW60377 P30566 AF067853 AAC21560 AF067854 AAC21561 AK225042 AK291091 BAF83780 AK293722 BAG57152 AK298187 BAG60458 AK300705 BAG62384 AK308662 BC000253 AAH00253 BC018881 BP298407 CR456368 CAG30254 CU012935 CAK54366 CU013223 CAK54665 DQ893326 ABM84252 DQ896642 ABM87641 KJ534763 AHW56403 KJ535007 AHW56646 KJ535020 AHW56659 KJ535041 AHW56680 KJ535056 AHW56695 S60710 AAC60603 X65867 CAA46696 XM_011529976 XP_011528278 XM_011529977 XP_011528279 XM_011529978 XP_011528280 XM_011529979 XP_011528281 XM_011529980 XP_011528282 XM_011529981 XP_011528283 XM_011529982 XP_011528284 XR_937824 XR_937825 XR_937826 NM_000026 NP_000017 NM_001123378 NP_001116850
Function Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
Tissue Specificity Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1.
Top Pathways Purine metabolism, Alanine, aspartate and glutamate metabolism

ADSL CRISPR/Cas9 KO Plasmid (h) - sc-404936 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL HDR Plasmid (h) - sc-404936-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL Double Nickase Plasmid (h) - sc-404936-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL Double Nickase Plasmid (h2) - sc-404936-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL CRISPR Activation Plasmid (h) - sc-404936-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL CRISPR Activation Plasmid (h2) - sc-404936-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL Lentiviral Activation Particles (h) - sc-404936-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL Lentiviral Activation Particles (h2) - sc-404936-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADSL siRNA (h) - sc-72457 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADSL shRNA Plasmid (h) - sc-72457-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADSL shRNA (h) Lentiviral Particles - sc-72457-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU070001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2905 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2905 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11975 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11975

ADSL siRNA (Human) - CRH0112 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADSL - MBS8200231 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADSL (NM_000026.2) - SHH232814 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADSL siRNA - orb260614 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADSL shRNA Plasmid (Human) - CHH0112 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADSL miRNA 3'UTR clone - MiUTR3H-09854 from Creative biogene

Species Reactivities Human

ADSL miRNA 3'UTR clone - MiUTR3H-09855 from Creative biogene

Species Reactivities Human
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