| Gene Symbol |
ACOX2
|
| Entrez Gene |
8309
|
| Alt Symbol |
BCOX, BRCACOX, BRCOX, THCCox
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA oxidase 2, branched chain
|
| Other Description |
3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase|THCA-CoA oxidase|acyl-Coenzyme A oxidase 2, branched chain|peroxisomal acyl-coenzyme A oxidase 2|peroxisomal branched chain acyl-CoA oxidase|trihydroxycoprostanoyl-CoA oxidase
|
| Swissprots |
A6NF16 Q99424 B2R8U5
|
| Accessions |
CAB65596 CBF60593 CBF65743 CBF73142 CBU85833 CBU90614 CBU96030 EAW65375 EAW65376 EAW65377 Q99424 AK298402 BAG60633 AK313512 BAG36292 BC033517 BC047700 AAH47700 BG698950 BI490007 X95190 CAA64489 XM_005265505 XP_005265562 XM_005265506 XP_005265563 XM_006713340 XP_006713403 XM_011534147 XP_011532449 XM_011534148 XP_011532450 NM_003500 NP_003491
|
| Function |
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.
|
| Subcellular Location |
Peroxisome.
|
| Tissue Specificity |
Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
|
| Top Pathways |
Primary bile acid biosynthesis, PPAR signaling pathway, Peroxisome
|
![Western Blot: ACOX2 Overexpression Lysate (Adult Normal) [NBP2-08001] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ACOX2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2872_ACOX2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08001-img0001.jpg)