Gene Symbol | PCK2 |
---|---|
Entrez Gene | 5106 |
Alt Symbol | PEPCK, PEPCK-M, PEPCK2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
Other Description | PEP carboxykinase|phosphoenolpyruvate carboxykinase [GTP], mitochondrial|phosphopyruvate carboxylase |
Swissprots | O43253 Q16822 Q9BV62 Q86U01 |
Accessions | BAD36844 CAA12234 CAA72272 EAW66115 Q16822 AK129934 AK301400 BAG62935 AK307913 AK311710 AK316206 BAH14577 BC001454 AAH01454 BQ957219 BU153045 BU623248 BX248272 CAD62600 CA444720 CN359636 CR456913 CAG33194 DA645036 DB028389 HY022221 X92720 CAA63380 XM_006720158 XP_006720221 XM_011536813 XP_011535115 NM_001018073 NP_001018083 NM_001291556 NP_001278485 NM_001308054 NP_001294983 NM_004563 NP_004554 |
Function | Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. {ECO:0000250}. |
Subcellular Location | Mitochondrion. |
Top Pathways | Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation |
PEPCK-M CRISPR/Cas9 KO Plasmid (h) - sc-400725 from Santa Cruz Biotechnology
|
||||||||
PEPCK-M HDR Plasmid (h) - sc-400725-HDR from Santa Cruz Biotechnology
|
||||||||
PEPCK-M Double Nickase Plasmid (h) - sc-400725-NIC from Santa Cruz Biotechnology
|
||||||||
PEPCK-M Double Nickase Plasmid (h2) - sc-400725-NIC-2 from Santa Cruz Biotechnology
|
||||||||
PEPCK-M CRISPR Activation Plasmid (h) - sc-400725-ACT from Santa Cruz Biotechnology
|
||||||||
PEPCK-M CRISPR Activation Plasmid (h2) - sc-400725-ACT-2 from Santa Cruz Biotechnology
|
||||||||
PEPCK-M Lentiviral Activation Particles (h) - sc-400725-LAC from Santa Cruz Biotechnology
|
||||||||
PEPCK-M Lentiviral Activation Particles (h2) - sc-400725-LAC-2 from Santa Cruz Biotechnology
|
||||||||
PEPCK-M siRNA (h) - sc-44912 from Santa Cruz Biotechnology
|
||||||||
PEPCK-M shRNA Plasmid (h) - sc-44912-SH from Santa Cruz Biotechnology
|
||||||||
PEPCK-M shRNA (h) Lentiviral Particles - sc-44912-V from Santa Cruz Biotechnology
|
||||||||
PCK2 RNAi - H00005106-R04 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU028511 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1533 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1534 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK1532 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN16479 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16479 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR01730 from Sigma-Aldrich
|
||||||||
PCK2 siRNA (Human) - CRH3398 from Cohesion Biosciences
|
||||||||
PCK2 RNAi - H00005106-R02 from Novus Biologicals
|
||||||||
shRNA set against Human PCK2 (NM_004563.2) - SHH371868 from Creative biogene
|
||||||||
shRNA set against Human PCK2(NM_004563.2) - SHR096914 from Creative biogene
|
||||||||
shRNA set against Human PCK2(NM_001018073.1) - SHR097104 from Creative biogene
|
||||||||
PCK2 shRNA Plasmid (Human) - CHH3398 from Cohesion Biosciences
|