Gene Symbol | HP |
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Entrez Gene | 280692 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | haptoglobin |
Other Description | zonulin |
Swissprots | Q2TBU0 |
Accessions | DAA19997 Q2TBU0 AJ271156 CAC00531 BC109668 AAI09669 NM_001040470 NP_001035560 |
Function | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Anti-Haptoglobin antibody - ab111220 from Abcam
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Haptoglobin antibody - GTX77237 from GeneTex
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Haptoglobin antibody - 70C-CR1338RAP from Fitzgerald
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Haptoglobin antibody - 70C-CR1337GAP from Fitzgerald
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Anti-Haptoglobin (native) polyclonal antibody - DPATB-H81632 from Creative Diagnostics
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Haptoglobin Polyclonal Antibody - PA1-29269 from Thermo Fisher Scientific
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Haptoglobin Polyclonal Antibody - PA1-29740 from Thermo Fisher Scientific
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Bovine Haptoglobin Antibody - 15751-05011 from AssayPro
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Bovine Haptoglobin Antibody (Biotin Conjugate) - 15751-05021 from AssayPro
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Monoclonal Antibody to Haptoglobin (Hpt) - MAA817Bo21 from Cloud-clone
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Polyclonal Antibody to Haptoglobin (Hpt) - PAA817Bo01 from Cloud-clone
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Haptoglobin - ASP-570 from Nordic BioSite
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Haptoglobin - ASP-571 from Nordic BioSite
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Haptoglobin Antibody - abx104827 from Abbexa
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Haptoglobin Antibody - abx104882 from Abbexa
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Polyclonal Antibody to Haptoglobin (Hpt) - PAA817Bo02 from Cloud-clone
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Haptoglobin (Hpt) Polyclonal Antibody - CAU27061 from Biomatik
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Haptoglobin (Hpt) Polyclonal Antibody - CAU27062 from Biomatik
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Anti-Haptoglobin monoclonal antibody - CABT-BL8834 from Creative Diagnostics
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Anti-Haptoglobin polyclonal antibody - CABT-BL8830 from Creative Diagnostics
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Anti-Haptoglobin polyclonal antibody - CABT-BL8838 from Creative Diagnostics
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