Gene Symbol | KRT20 |
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Entrez Gene | 54474 |
Alt Symbol | CD20, CK-20, CK20, K20, KRT21 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 20, type I |
Other Description | cytokeratin 20|cytokeratin-20|keratin, type I cytoskeletal 20|keratin-20|protein IT |
Swissprots | B2R6W7 P35900 |
Accessions | CAA51913 EAW60686 P35900 AK312744 BAG35614 BC031559 AAH31559 DA426874 DB242980 DQ890783 ABM81709 DQ896754 ABM87753 X73502 CAA51914 NM_019010 NP_061883 |
Function | Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:1696264}. |
Tissue Specificity | Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa. {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:1696264}. |
Cytokeratin 20 CRISPR/Cas9 KO Plasmid (h) - sc-401153 from Santa Cruz Biotechnology
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Cytokeratin 20 HDR Plasmid (h) - sc-401153-HDR from Santa Cruz Biotechnology
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Cytokeratin 20 Double Nickase Plasmid (h) - sc-401153-NIC from Santa Cruz Biotechnology
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Cytokeratin 20 Double Nickase Plasmid (h2) - sc-401153-NIC-2 from Santa Cruz Biotechnology
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Cytokeratin 20 CRISPR Activation Plasmid (h) - sc-401153-ACT from Santa Cruz Biotechnology
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Cytokeratin 20 CRISPR Activation Plasmid (h2) - sc-401153-ACT-2 from Santa Cruz Biotechnology
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Cytokeratin 20 Lentiviral Activation Particles (h) - sc-401153-LAC from Santa Cruz Biotechnology
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Cytokeratin 20 Lentiviral Activation Particles (h2) - sc-401153-LAC-2 from Santa Cruz Biotechnology
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Cytokeratin 20 siRNA (h) - sc-43313 from Santa Cruz Biotechnology
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Cytokeratin 20 shRNA Plasmid (h) - sc-43313-SH from Santa Cruz Biotechnology
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Cytokeratin 20 shRNA (h) Lentiviral Particles - sc-43313-V from Santa Cruz Biotechnology
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Cytokeratin 20 RNAi - H00054474-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11369 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11369 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03672 from Sigma-Aldrich
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KRT20 siRNA (Human) - CRJ0081 from Cohesion Biosciences
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shRNA set against Human KRT20 (NM_019010.2) - SHH327339 from Creative biogene
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Human KRT20 siRNA - orb270582 from Biorbyt
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KRT20 shRNA Plasmid (Human) - CHJ0081 from Cohesion Biosciences
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KRT20 miRNA 3'UTR clone - MiUTR3H-09852 from Creative biogene
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