Gene Symbol | SEPHS1 |
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Entrez Gene | 22929 |
Alt Symbol | SELD, SPS, SPS1 |
Species | Human |
Gene Type | protein-coding |
Description | selenophosphate synthetase 1 |
Other Description | selenide, water dikinase 1|selenium donor protein 1|selenophosphate synthase 1|selenophosphate synthetase 1 +E9|selenophosphate synthetase 1 +E9a|selenophosphate synthetase 1 delta E2|selenophosphate synthetase 1 delta E8|selenophosphate synthetase 1 major |
Swissprots | Q9BVT4 Q5T5U8 D6PSQ9 D3DRS9 B4DWK0 P49903 Q5T5U9 |
Accessions | CBX51405 EAW86289 EAW86290 EAW86291 EAW86292 EAW86293 P49903 AK125066 AK297129 BAG59633 AK301568 BAG63062 AK309829 AL557595 AL579174 BC000941 AAH00941 BC063816 AAH63816 BC064610 CT000832 DQ894137 ABM85063 GU954545 ADF78120 GU954546 ADF78121 GU954547 ADF78122 GU954548 ADF78123 GU954549 ADF78124 U34044 AAA87567 XM_006717433 XP_006717496 NM_001195602 NP_001182531 NM_001195604 NP_001182533 NM_012247 NP_036379 |
Function | Synthesizes selenophosphate from selenide and ATP. {ECO:0000269|PubMed:7665581}. |
Subcellular Location | Isoform 3: Cytoplasm. |
Tissue Specificity | Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. {ECO:0000269|PubMed:20471958}. |
Top Pathways | Selenocompound metabolism |
SEPHS1 CRISPR/Cas9 KO Plasmid (h) - sc-408203 from Santa Cruz Biotechnology
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SEPHS1 HDR Plasmid (h) - sc-408203-HDR from Santa Cruz Biotechnology
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SEPHS1 Double Nickase Plasmid (h) - sc-408203-NIC from Santa Cruz Biotechnology
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SEPHS1 Double Nickase Plasmid (h2) - sc-408203-NIC-2 from Santa Cruz Biotechnology
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SEPHS1 CRISPR Activation Plasmid (h) - sc-408203-ACT from Santa Cruz Biotechnology
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SEPHS1 CRISPR Activation Plasmid (h2) - sc-408203-ACT-2 from Santa Cruz Biotechnology
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SEPHS1 Lentiviral Activation Particles (h) - sc-408203-LAC from Santa Cruz Biotechnology
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SEPHS1 Lentiviral Activation Particles (h2) - sc-408203-LAC-2 from Santa Cruz Biotechnology
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SEPHS1 siRNA (h) - sc-90338 from Santa Cruz Biotechnology
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SEPHS1 shRNA Plasmid (h) - sc-90338-SH from Santa Cruz Biotechnology
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SEPHS1 shRNA (h) Lentiviral Particles - sc-90338-V from Santa Cruz Biotechnology
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SEPHS1 RNAi - H00022929-R02 from Novus Biologicals
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MISSION® esiRNA - EHU107861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19093 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19093 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07751 from Sigma-Aldrich
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SEPHS1 siRNA (Human) - CRH7880 from Cohesion Biosciences
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SEPHS1 - MBS8228858 from MyBioSource
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Human SEPHS1 siRNA - orb268382 from Biorbyt
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SEPHS1 shRNA Plasmid (Human) - CHH7880 from Cohesion Biosciences
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SEPHS1 miRNA 3'UTR clone - MiUTR3H-03720 from Creative biogene
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