| Gene Symbol |
Kras
|
| Entrez Gene |
16653
|
| Alt Symbol |
AI929937, K-ras, Ki-ras, Kras-2, Kras2, p21B, ras
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
|
| Other Description |
GTPase KRas|K-Ras 2|Kirsten rat sarcoma oncogene 2, expressed|c-K-ras|c-Ki-ras|p21 protein
|
| Swissprots |
P08643 P04200 P32883
|
| Accessions |
AAA40037 AAO46052 CAA26295 CAA26296 CAA33897 CDL93478 EDL10686 P32883 AK155064 BAE33023 AK164065 BAE37609 AY487807 AAS58056 BC004642 AAH04642 BC010202 AAH10202 BC014700 BC031623 BC119495 AAI19496 BC141051 AAI41052 U76425 U76426 X00485 CAA25160 XM_006506918 XP_006506981 XM_006506919 XP_006506982 XM_006536039 XP_006536102 XM_006536040 XP_006536103 NM_021284 NP_067259
|
| Function |
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation (PubMed:6474169, PubMed:1352876). {ECO:0000250|UniProtKB:P01116, ECO:0000269|PubMed:1352876, ECO:0000269|PubMed:6474169}.
|
| Subcellular Location |
Cell membrane {ECO:0000250|UniProtKB:P01116}; Lipid-anchor {ECO:0000250|UniProtKB:P01116}; Cytoplasmic side {ECO:0000250|UniProtKB:P01116}. Cytoplasm {ECO:0000250|UniProtKB:P01116}.
|
| Top Pathways |
Axon guidance, Tight junction, VEGF signaling pathway, Gap junction, Natural killer cell mediated cytotoxicity
|