CHST1

Gene Symbol CHST1
Entrez Gene 8534
Alt Symbol C6ST, GST-1, KS6ST, KSGal6ST, KSST
Species Human
Gene Type protein-coding
Description carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
Other Description carbohydrate (chondroitin 6/keratan) sulfotransferase 1|carbohydrate sulfotransferase 1|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1
Swissprots D3DQP2 O43916
Accessions AAP88041 EAW68034 EAW68035 EAW68036 EAW68037 EAW68038 EAW68039 O43916 AB003791 BAA24840 AF090137 AAD19878 AI793094 AK311168 BC022567 AAH22567 BC028235 AAH28235 BI917296 DA193787 DB493321 U65637 AAC28776 XM_006718356 XP_006718419 XR_428858 NM_003654 NP_003645
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N- acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. {ECO:0000269|PubMed:10330415, ECO:0000269|PubMed:10642612}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed at low level. Expressed in brain and skeletal muscle. Expressed by high endothelial cells (HEVs) and leukocytes. {ECO:0000269|PubMed:11310842, ECO:0000269|PubMed:9405439}.
Top Pathways Glycosaminoglycan biosynthesis - keratan sulfate

CHST1 (A-2) - sc-365021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHST1 (A-2): sc-365021. Western blot analysis of CHST1 expression in non-transfected: sc-117752 (A) and human CHST1 transfected: sc-114756 (B) 293T whole cell lysates.

CHST1 (E-3) - sc-271599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHST1 (E-3): sc-271599. Western blot analysis of CHST1 expression in non-transfected: sc-117752 (A) and human CHST1 transfected: sc-114756 (B) 293T whole cell lysates.

CHST1 (H-107) - sc-135030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CHST1 (H-107): sc-135030. Western blot analysis of CHST1 expression in non-transfected: sc-117752 (A) and human CHST1 transfected: sc-114756 (B) 293T whole cell lysates.

CHST1 (P-18) - sc-65030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CHST1 (P-18): sc-65030. Western blot analysis of CHST1 expression in non-transfected 293T: sc-117752 (A), human CHST1 transfected 293T: sc-114756 (B) and HeLa (C) whole cell lysates.

CHST1 (E-8) - sc-365022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CHST1 (E-8): sc-365022. Western blot analysis of CHST1 expression in non-transfected: sc-117752 (A) and human CHST1 transfected: sc-114756 (B) 293T whole cell lysates.

CHST1 (S-20) - sc-65031 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CHST1 (W-18) - sc-65032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CHST1 (W-18): sc-65032. Western blot analysis of CHST1 expression in non-transfected: sc-117752 (A) and human CHST1 transfected: sc-114756 (B) 293T whole cell lysates.

Keratan sulfate (4B3/D10) - sc-73518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal

Anti-Keratan Sulfate antibody - ab98857 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Keratan Sulfate antibody (ab98857) at 1 µg/ml + Human fetal kidney lysate at 10 µg

Anti-Keratan Sulfate antibody [4B3/D10] - ab52141 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4B3/D10

Anti-CHST1 Antibody (aa341-375, clone RB47041) - LS-C344700 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Clone RB47041
Western blot of lysates from zebra fish muscle, Zebrafish tissue lysate (from left to right) with (DANRE) chst1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.

Anti-CHST1 Antibody - LS-C143677 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CHST1 Antibody (aa126-171) - LS-C313711 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CHST1 Antibody (aa24-411) - LS-C125246 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-CHST1 Antibody (aa251-300) - LS-C107997 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CHST1 antibody LS-C107997 Western blot of Fetal Kidney lysate.

Anti-CHST1 Antibody (aa74-123) - LS-C80727 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CHST1 antibody LS-C80727 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.

Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody - NBP1-62542 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody [NBP1-62542] - Jurkat tissue lysate at a concentration of 1.25ug/ml.

Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody - AF5316 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Western blot shows lysates of human tonsil tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Carbohydrate Sulfotransferase 1/CHST1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5316) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Carbohydrate Sulfotransferase 1/CHST1 at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody (543128) - MAB5316 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 543128

Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody - NBP1-62370 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody [NBP1-62370] - Human Fetal Heart, Antibody Dilution: 1.0 ug/ml.

Carbohydrate Sulfotransferase 1/CHST1/KS6ST Antibody [Biotin] - BAF5316 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Keratan Sulfate Polyclonal Antibody - bs-4144R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CHST1 antibody produced in rabbit - AV45495 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHST1: <B>Cat. No. AV45495</B>: Immunohistochemistry of CHST1 in Human Muscle tissue with CHST1 antibody at 4-8 μg/mL.

Anti-CHST1 antibody produced in rabbit - SAB2105639 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHST1: <B>Cat. No. SAB2105639</B>: CHST1 in Fetal Kidney cell lysates with CHST1 antibody at 1.0 μg/mL.

CHST1 antibody - N-terminal region (ARP45495_T100) - ARP45495_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more