ADA

Gene Symbol ADA
Entrez Gene 280712
Alt Symbol -
Species Bovine
Gene Type protein-coding
Description adenosine deaminase
Other Description adenosine aminohydrolase
Swissprots Q9MYY1 P56658
Accessions CBX85613 DAA23102 P56658 AF280603 AAF91430 BC146169 AAI46170 NM_173887 NP_776312
Function Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte- epithelial cell adhesion (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasmic vesicle lumen {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion. {ECO:0000250}.
Top Pathways Primary immunodeficiency, Purine metabolism

Native Bovine adenosine deaminase therapeutic protein (Pegademase bovine) - ADA-P036B from Creative Biomart

Category Protein
Source bovine intestine
Species Bovine

Recombinant Bovine Adenosine deaminase(ADA) - CSB-YP001268BO CSB-EP001268BO CSB-BP001268BO CSB-MP001268BO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Bovine

Adenosine deaminase (add) - MBS963317 from MyBioSource

Category Protein
Prices $1,795.00, $1,795.00, $2,255.00, $2,255.00
Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Bovine

Pegademase bovine - TP-025CL from Creative Biolabs

Species Bovine
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