Gene Symbol | CDC45 |
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Entrez Gene | 8318 |
Alt Symbol | CDC45L, CDC45L2, PORC-PI-1 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 45 |
Other Description | CDC45 cell division cycle 45 homolog|CDC45-related protein|cell division control protein 45 homolog|cell division cycle 45 homolog|cell division cycle 45-like 2|human CDC45 |
Swissprots | Q9UP68 Q6UW54 E9PDH7 B4DDB4 O75419 B4DDU3 O60856 Q20WK8 |
Accessions | AAS66985 CCV01316 EAX03036 O75419 AF053074 AAC27289 AF062495 AAC67521 AF081535 AAD08998 AJ223728 CAA11530 AK293123 BAG56675 AK293338 BAG56854 AK302590 BAG63843 AK303274 BAG64354 AY358971 AAQ89330 BC006232 AAH06232 BC010022 AAH10022 BM751026 BT006792 AAP35438 CT841513 CAJ86443 CU012976 CAK54407 CU013264 CAK54706 DQ890621 ABM92238 DQ892651 ABM83577 DQ893790 ABM84716 DQ895890 ABM86816 HY016491 XM_005261285 XP_005261342 XM_005261286 XP_005261343 XM_011530415 XP_011528717 XM_011530416 XP_011528718 XM_011530417 XP_011528719 XM_011530418 XP_011528720 XM_011530419 XP_011528721 XR_937930 NM_001178010 NP_001171481 NM_001178011 NP_001171482 NM_003504 NP_003495 |
Function | Required for initiation of chromosomal DNA replication. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Widely expressed, highest levels are found in adult testis and thymus and in fetal liver. |
Top Pathways | Cell cycle |
Cdc45 CRISPR/Cas9 KO Plasmid (h) - sc-401882 from Santa Cruz Biotechnology
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Cdc45 HDR Plasmid (h) - sc-401882-HDR from Santa Cruz Biotechnology
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Cdc45 Double Nickase Plasmid (h) - sc-401882-NIC from Santa Cruz Biotechnology
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Cdc45 Double Nickase Plasmid (h2) - sc-401882-NIC-2 from Santa Cruz Biotechnology
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Cdc45 CRISPR Activation Plasmid (h) - sc-401882-ACT from Santa Cruz Biotechnology
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Cdc45 CRISPR Activation Plasmid (h2) - sc-401882-ACT-2 from Santa Cruz Biotechnology
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Cdc45 Lentiviral Activation Particles (h) - sc-401882-LAC from Santa Cruz Biotechnology
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Cdc45 Lentiviral Activation Particles (h2) - sc-401882-LAC-2 from Santa Cruz Biotechnology
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Cdc45 siRNA (h) - sc-35044 from Santa Cruz Biotechnology
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Cdc45 shRNA Plasmid (h) - sc-35044-SH from Santa Cruz Biotechnology
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Cdc45 shRNA (h) Lentiviral Particles - sc-35044-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU003381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5793 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5793 from Sigma-Aldrich
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CDC45 siRNA (Human) - CRH5441 from Cohesion Biosciences
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CDC45L RNAi - H00008318-R01 from Novus Biologicals
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CDC45 - MBS8216146 from MyBioSource
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shRNA set against Human CDC45 (NM_003504.3) - SHH259941 from Creative biogene
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shRNA set against Human CDC45L(NM_003504.3) - SHG161965 from Creative biogene
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Human CDC45 siRNA - orb265943 from Biorbyt
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CDC45 shRNA Plasmid (Human) - CHH5441 from Cohesion Biosciences
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CDC45 miRNA 3'UTR clone - MiUTR1H-01963 from Creative biogene
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