Gene Symbol | RAD54B |
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Entrez Gene | 25788 |
Alt Symbol | RDH54 |
Species | Human |
Gene Type | protein-coding |
Description | RAD54 homolog B (S. cerevisiae) |
Other Description | DNA repair and recombination protein RAD54B |
Swissprots | F6WBS8 O95073 Q8N4S5 Q9Y620 |
Accessions | EAW91712 EAW91713 EAW91714 Q9Y620 AF086020 AF112481 AAD34331 AK290437 BAF83126 AK307516 AL133578 CAB63724 BC001965 AAH01965 BC020668 BC033710 AAH33710 BF766767 BP872374 CN356732 DA553267 NM_001205262 NP_001192191 NM_001205263 NP_001192192 NM_012415 NP_036547 NM_006550 NM_134434 |
Function | Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group. {ECO:0000269|PubMed:11782437, ECO:0000269|PubMed:11884632}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon. {ECO:0000269|PubMed:10362364}. |
Top Pathways | Homologous recombination |
Rad54B CRISPR/Cas9 KO Plasmid (h) - sc-403794 from Santa Cruz Biotechnology
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Rad54B HDR Plasmid (h) - sc-403794-HDR from Santa Cruz Biotechnology
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Rad54B Double Nickase Plasmid (h) - sc-403794-NIC from Santa Cruz Biotechnology
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Rad54B Double Nickase Plasmid (h2) - sc-403794-NIC-2 from Santa Cruz Biotechnology
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Rad54B CRISPR Activation Plasmid (h) - sc-403794-ACT from Santa Cruz Biotechnology
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Rad54B CRISPR Activation Plasmid (h2) - sc-403794-ACT-2 from Santa Cruz Biotechnology
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Rad54B Lentiviral Activation Particles (h) - sc-403794-LAC from Santa Cruz Biotechnology
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Rad54B Lentiviral Activation Particles (h2) - sc-403794-LAC-2 from Santa Cruz Biotechnology
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Rad54B siRNA (h) - sc-37401 from Santa Cruz Biotechnology
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Rad54B shRNA Plasmid (h) - sc-37401-SH from Santa Cruz Biotechnology
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Rad54B shRNA (h) Lentiviral Particles - sc-37401-V from Santa Cruz Biotechnology
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RAD54B RNAi - H00025788-R02 from Novus Biologicals
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RAD54B RNAi - H00025788-R01 from Novus Biologicals
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MISSION® esiRNA - EHU026831 from Sigma-Aldrich
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MISSION® esiRNA - EHU014581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17904 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17904 from Sigma-Aldrich
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RAD54B siRNA (Human) - CRH8493 from Cohesion Biosciences
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FSBP - MBS8210965 from MyBioSource
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RAD54B - MBS8221425 from MyBioSource
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shRNA set against Human RAD54B (NM_012415.3) - SHH389076 from Creative biogene
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Human RAD54B siRNA - orb268995 from Biorbyt
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RAD54B shRNA Plasmid (Human) - CHH8493 from Cohesion Biosciences
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RAD54B miRNA 3'UTR clone - MiUTR3H-06699 from Creative biogene
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