Gene Symbol | GDAP1 |
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Entrez Gene | 54332 |
Alt Symbol | CMT4, CMT4A, CMTRIA |
Species | Human |
Gene Type | protein-coding |
Description | ganglioside induced differentiation associated protein 1 |
Other Description | Charcot-Marie-Tooth neuropathy 4A|ganglioside differentiation associated protein 1|ganglioside-induced differentiation-associated protein 1 |
Swissprots | E7FJF3 E7FJF4 A8K957 Q8TB36 |
Accessions | EAW87032 EAW87033 Q8TB36 AB551556 BAJ65577 AB551557 BAJ65578 AB551558 BAJ65579 AK292572 BAF85261 AK295594 BAG58484 AL110252 BC024939 AAH24939 BC035450 BC036496 DB505741 Y17849 CAA76892 XM_011517551 XP_011515853 XM_011517552 XP_011515854 NM_001040875 NP_001035808 NM_018972 NP_061845 NR_046346 |
Function | Regulates the mitochondrial network by promoting mitochondrial fission. {ECO:0000269|PubMed:16172208}. |
Subcellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in whole brain and spinal cord. Predominant expression in central tissues of the nervous system not only in neurons but also in Schwann cells. {ECO:0000269|PubMed:11743580, ECO:0000269|PubMed:16172208}. |
GDAP1 CRISPR/Cas9 KO Plasmid (h) - sc-412270 from Santa Cruz Biotechnology
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GDAP1 HDR Plasmid (h) - sc-412270-HDR from Santa Cruz Biotechnology
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GDAP1 Double Nickase Plasmid (h) - sc-412270-NIC from Santa Cruz Biotechnology
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GDAP1 Double Nickase Plasmid (h2) - sc-412270-NIC-2 from Santa Cruz Biotechnology
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GDAP1 CRISPR Activation Plasmid (h) - sc-412270-ACT from Santa Cruz Biotechnology
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GDAP1 CRISPR Activation Plasmid (h2) - sc-412270-ACT-2 from Santa Cruz Biotechnology
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GDAP1 Lentiviral Activation Particles (h) - sc-412270-LAC from Santa Cruz Biotechnology
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GDAP1 Lentiviral Activation Particles (h2) - sc-412270-LAC-2 from Santa Cruz Biotechnology
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GDAP1 siRNA (h) - sc-77458 from Santa Cruz Biotechnology
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GDAP1 shRNA Plasmid (h) - sc-77458-SH from Santa Cruz Biotechnology
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GDAP1 shRNA (h) Lentiviral Particles - sc-77458-V from Santa Cruz Biotechnology
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GDAP1 RNAi - H00054332-R02 from Novus Biologicals
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MISSION® esiRNA - EHU046541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9204 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9204 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11774 from Sigma-Aldrich
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GDAP1 siRNA (Human) - CRJ0039 from Cohesion Biosciences
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GDAP1 RNAi - H00054332-R01 from Novus Biologicals
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GDAP1 - MBS8216333 from MyBioSource
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shRNA set against Human GDAP1 (NM_018972.2) - SHH300190 from Creative biogene
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shRNA set against Human GDAP1(NM_018972.2) - SHH080867 from Creative biogene
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Human GDAP1 siRNA - orb270540 from Biorbyt
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GDAP1 shRNA Plasmid (Human) - CHJ0039 from Cohesion Biosciences
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GDAP1 miRNA 3'UTR clone - MiUTR1H-03994 from Creative biogene
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