Gene Symbol | CD38 |
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Entrez Gene | 952 |
Alt Symbol | ADPRC 1, T10 |
Species | Human |
Gene Type | protein-coding |
Description | CD38 molecule |
Other Description | 2'-phospho-ADP-ribosyl cyclase|2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase|2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|CD38 antigen (p45)|NAD(+) nucleosidase|cADPr hydrolase 1|cyclic ADP-ribose hydrolase 1 |
Swissprots | P28907 Q96HY4 O00122 O00121 |
Accessions | AAY99634 BAA18966 CDM22270 EAW92745 EAW92746 P28907 AA417096 AK297592 BAG59979 AK303169 BAG64268 AK313268 BAG36077 BC007964 AAH07964 CD688069 D84276 BAA18964 D84277 BAA18965 DQ893184 ABM84110 EU176777 ABW03578 M34461 AAA68482 XR_241678 NM_001775 NP_001766 |
Function | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. {ECO:0000269|PubMed:9074508}. |
Top Pathways | Hematopoietic cell lineage, Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Epstein-Barr virus infection |
CD38 overexpression lysate - LY419752 from Acris Antibodies
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CD38 293 Cell Lysate - 409251 from ABBIOTEC
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CD38 Overexpression Lysate (Native) - NBL1-08942 from Novus Biologicals
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CD38 Over-expression Lysate Product - GWB-4CF843 from Genway Biotech
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Cynomolgus CD38 HEK293 Cell Lysate (WB positive control) - 90050-C02HL-300 from Sino Biological
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Cynomolgus CD38 HEK293 Cell Lysate (WB positive control) - 90050-C08HL-300 from Sino Biological
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Human CD38 HEK293 Cell Lysate (WB positive control) - 10818-H32HL-300 from Sino Biological
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Human CD38 HEK293 Cell Lysate (WB positive control) - 10818-H08HL-300 from Sino Biological
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Human CD38 Human Cells Transfected Lysate (positive control) (denatured) - orb174135 from Biorbyt
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Cynomolgus CD38 Human Cells Transfected Lysate (positive control) (denatured) - orb174276 from Biorbyt
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Human CD38 Human Cells Transfected Lysate (positive control) (denatured) - orb173095 from Biorbyt
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Cynomolgus CD38 Human Cells Transfected Lysate (positive control) (denatured) - orb174826 from Biorbyt
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Panoply™ Human CD38 Knockdown Stable Cell Line - CSC-DC002744 from Creative biogene
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CD38 Knockout Cell Line-HeLa - CSC-RT2055 from Creative biogene
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CD38 KO Cell Lysate-HeLa - CLKO-1916 from Creative biogene
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