PLA2G5

Gene Symbol PLA2G5
Entrez Gene 5322
Alt Symbol FRFB, GV-PLA2, PLA2-10, hVPLA(2)
Species Human
Gene Type protein-coding
Description phospholipase A2, group V
Other Description Ca2+-dependent phospholipase A2|calcium-dependent phospholipase A2|phosphatidylcholine 2-acylhydrolase 5
Swissprots Q8N435 P39877
Accessions AAR92480 EAW94911 EAW94912 EAW94913 P39877 AK097693 BAG53516 AV709457 BC036792 AAH36792 BM684907 BM705479 BX648966 U03090 AAC28886 XM_005245891 XP_005245948 XM_005245892 XP_005245949 XM_005245893 XP_005245950 XM_006710696 XP_006710759 XM_011541584 XP_011539886 XM_011541585 XP_011539887 XM_011541586 XP_011539888 XM_011541587 XP_011539889 XM_011541588 XP_011539890 XM_011541589 XP_011539891 XM_011541590 XP_011539892 XM_011541591 XP_011539893 XM_011541592 XP_011539894 NM_000929 NP_000920
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
Subcellular Location Secreted.
Tissue Specificity Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level). {ECO:0000269|PubMed:22137173}.
Top Pathways Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism

group V PLA 2 CRISPR/Cas9 KO Plasmid (h) - sc-409663 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 HDR Plasmid (h) - sc-409663-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 Double Nickase Plasmid (h) - sc-409663-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 Double Nickase Plasmid (h2) - sc-409663-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 CRISPR Activation Plasmid (h) - sc-409663-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 CRISPR Activation Plasmid (h2) - sc-409663-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 Lentiviral Activation Particles (h) - sc-409663-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 Lentiviral Activation Particles (h2) - sc-409663-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

group V PLA 2 siRNA (h) - sc-44023 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

group V PLA 2 shRNA Plasmid (h) - sc-44023-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

group V PLA 2 shRNA (h) Lentiviral Particles - sc-44023-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Secretory phospholipase A2 Type V RNAi - H00005322-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU050591 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16900 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16900 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08671 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08671

PLA2G5 siRNA (Human) - CRH3563 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLA2G5 (NM_000929.2) - SHH376880 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLA2G5(NM_000929.2) - SHR118096 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLA2G5 siRNA - orb264065 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLA2G5 shRNA Plasmid (Human) - CHH3563 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLA2G5 miRNA 3'UTR clone - MiUTR1H-07963 from Creative biogene

Species Reactivities Human
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