Gene Symbol | PNLIPRP2 |
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Entrez Gene | 5408 |
Alt Symbol | PLRP2 |
Species | Human |
Gene Type | protein-coding |
Description | pancreatic lipase-related protein 2 |
Other Description | PL-RP2|galactolipase |
Swissprots | A8K627 Q6IB55 P54317 |
Accessions | EAW49447 EAW49448 P54317 AA367174 AK291492 BAF84181 AK307745 AK308508 AK308511 AK308521 BC005989 AAH05989 BP325072 BQ786898 BU078199 CR456949 CAG33230 DQ893126 ABM84052 DQ896403 ABM87402 M93284 AAA59533 NM_005396 NP_005387 NR_103727 |
Function | Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Acts preferentially on monoglycerides, phospholipids and galactolipids. Contributes to milk fat hydrolysis. {ECO:0000269|PubMed:18702514, ECO:0000269|PubMed:19824014, ECO:0000269|PubMed:20083229}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:18702514, ECO:0000269|PubMed:19824014}. |
Tissue Specificity | Pancreas. |
Top Pathways | Pancreatic secretion, Fat digestion and absorption, Glycerolipid metabolism |
PLRP2 CRISPR/Cas9 KO Plasmid (h) - sc-409664 from Santa Cruz Biotechnology
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PLRP2 HDR Plasmid (h) - sc-409664-HDR from Santa Cruz Biotechnology
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PLRP2 Double Nickase Plasmid (h) - sc-409664-NIC from Santa Cruz Biotechnology
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PLRP2 Double Nickase Plasmid (h2) - sc-409664-NIC-2 from Santa Cruz Biotechnology
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PLRP2 CRISPR Activation Plasmid (h) - sc-409664-ACT from Santa Cruz Biotechnology
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PLRP2 CRISPR Activation Plasmid (h2) - sc-409664-ACT-2 from Santa Cruz Biotechnology
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PLRP2 Lentiviral Activation Particles (h) - sc-409664-LAC from Santa Cruz Biotechnology
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PLRP2 Lentiviral Activation Particles (h2) - sc-409664-LAC-2 from Santa Cruz Biotechnology
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PLRP2 siRNA (h) - sc-76174 from Santa Cruz Biotechnology
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PLRP2 shRNA Plasmid (h) - sc-76174-SH from Santa Cruz Biotechnology
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PLRP2 shRNA (h) Lentiviral Particles - sc-76174-V from Santa Cruz Biotechnology
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Pancreatic Lipase Related Protein 2 RNAi - H00005408-R01 from Novus Biologicals
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MISSION® esiRNA - EHU027661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17048 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17048 from Sigma-Aldrich
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PNLIPRP2 siRNA (Human) - CRH3618 from Cohesion Biosciences
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shRNA set against Human PNLIPRP2 (NM_005396.4) - SHH378616 from Creative biogene
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shRNA set against Human PNLIPRP2(NM_005396.4) - SHR124692 from Creative biogene
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PNLIPRP2 shRNA Plasmid (Human) - CHH3618 from Cohesion Biosciences
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PNLIPRP2 miRNA 3'UTR clone - MiUTR1H-08042 from Creative biogene
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