NT5M

Gene Symbol	NT5M
Entrez Gene	56953
Alt Symbol	dNT-2, dNT2, mdN
Species	Human
Gene Type	protein-coding
Description	5',3'-nucleotidase, mitochondrial
Other Description	5' nucleotidase, mitochondrial|5'(3')-deoxyribonucleotidase, mitochondrial|5(3)-deoxyribonucleotidase|deoxy-5'-nucleotidase 2|mitochondrial 5' nucleotidase
Swissprots	Q9NPB1
Accessions	CAB99251 EAW55710 Q9NPB1 AF210652 AAF87076 AL526346 BC035838 AAH35838 DQ323995 ABC88597 XM_005256731 XP_005256788 XM_005256732 XP_005256789 XM_005256733 XP_005256790 XM_005256734 XP_005256791 XM_005256737 XP_005256794 XM_011523961 XP_011522263 XM_011523962 XP_011522264 XM_011523963 XP_011522265 XM_011523964 XP_011522266 XM_011523965 XP_011522267 XM_011523966 XP_011522268 XM_011523967 XP_011522269 NM_020201 NP_064586
Function	Dephosphorylates specifically the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. {ECO:0000269|PubMed:10899995}.
Subcellular Location	Mitochondrion {ECO:0000269|PubMed:10899995}.
Tissue Specificity	Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas. {ECO:0000269|PubMed:10899995}.
Top Pathways	Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

dNT-2 CRISPR/Cas9 KO Plasmid (h) - sc-412736 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 HDR Plasmid (h) - sc-412736-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 Double Nickase Plasmid (h) - sc-412736-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 Double Nickase Plasmid (h2) - sc-412736-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 CRISPR Activation Plasmid (h) - sc-412736-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 CRISPR Activation Plasmid (h2) - sc-412736-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 Lentiviral Activation Particles (h) - sc-412736-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 Lentiviral Activation Particles (h2) - sc-412736-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

dNT-2 siRNA (h) - sc-38997 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

dNT-2 shRNA Plasmid (h) - sc-38997-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

dNT-2 shRNA (h) Lentiviral Particles - sc-38997-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NT5M RNAi - H00056953-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU142141 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP0375 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0373 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0374 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN15556 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15556 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05951 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr05951

NT5M siRNA (Human) - CRJ1252 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human NT5M (NM_020201.3) - SHH355628 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human NT5M(NM_020201.3) - SHR024432 from Creative biogene Category siRNA Species Reactivities Human

NT5M shRNA Plasmid (Human) - CHJ1252 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

NT5M miRNA 3'UTR clone - MiUTR1H-06941 from Creative biogene Species Reactivities Human

Search more