| Gene Symbol |
WDR18
|
| Entrez Gene |
57418
|
| Alt Symbol |
Ipi3, R32184_1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 18
|
| Other Description |
Involved in Processing ITS2 3 homolog|WD repeat-containing protein 18
|
| Swissprots |
Q9BWR2 O60390 Q9BV38
|
| Accessions |
AAC12679 EAW69578 Q9BV38 AK131009 AL560525 BC000040 AAH00040 BC001648 AAH01648 CB991338 NM_024100 NP_077005
|
| Function |
May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {ECO:0000250, ECO:0000269|PubMed:22872859}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions. {ECO:0000250}.
|