GNPTAB

Gene Symbol GNPTAB
Entrez Gene 79158
Alt Symbol GNPTA, ICD
Species Human
Gene Type protein-coding
Description N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Other Description GlcNAc phosphotransferase|N-acetylglucosamine-1-phosphotransferase subunits alpha/beta|UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta|UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosamine|glcNAc-1-phosphotransferase subunits alpha/beta|glucosamine (UDP-N-acetyl)-lysosomal-enzyme N-acetylglucosamine phosphotransferase|stealth protein GNPTAB
Swissprots Q9ULL2 Q96N13 Q86TQ2 A2RRQ9 Q6IPW5 Q3T906 Q3ZQK2
Accessions EAW97682 EAW97683 EAW97684 Q3T906 AB033034 BAA86522 AI418963 AI479646 AK001821 BAA91926 AK056137 BAB71102 AL359588 CAB94874 AL832172 AM085438 CAJ30014 AY687932 AAV98624 BC002779 AAH02779 BC042615 AAH42615 BC071687 AAH71687 BC094884 AAH94884 BC131787 AAI31788 BP276948 BU754017 CR749871 CAH18711 XM_006719593 XP_006719656 XM_011538731 XP_011537033 NM_024312 NP_077288
Function Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment. {ECO:0000269|PubMed:19955174, ECO:0000269|PubMed:23733939}.
Subcellular Location N-acetylglucosamine-1-phosphotransferase subunit alpha: Golgi apparatus membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:16120602}.
Top Pathways Lysosome

GNPTAB CRISPR/Cas9 KO Plasmid (h) - sc-405411 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB HDR Plasmid (h) - sc-405411-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB Double Nickase Plasmid (h) - sc-405411-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB Double Nickase Plasmid (h2) - sc-405411-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB CRISPR Activation Plasmid (h) - sc-405411-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB CRISPR Activation Plasmid (h2) - sc-405411-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB Lentiviral Activation Particles (h) - sc-405411-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB Lentiviral Activation Particles (h2) - sc-405411-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GNPTAB siRNA (h) - sc-95992 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GNPTAB shRNA Plasmid (h) - sc-95992-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GNPTAB shRNA (h) Lentiviral Particles - sc-95992-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU032491 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU103521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9446 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9446 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10289 from Sigma-Aldrich

Category miRNA

GNPTAB siRNA (Human) - CRJ2337 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNPTAB - MBS8201665 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GNPTAB (NM_024312.4) - SHH305090 from Creative biogene

Category siRNA
Species Reactivities Human

GNPTAB shRNA Plasmid (Human) - CHJ2337 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GNPTAB miRNA 3'UTR clone - MiUTR3H-09502 from Creative biogene

Species Reactivities Human
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