| Gene Symbol |
IL12B
|
| Entrez Gene |
3593
|
| Alt Symbol |
CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interleukin 12B
|
| Other Description |
CLMF p40|IL-12 subunit p40|IL12, subunit p40|NK cell stimulatory factor chain 2|cytotoxic lymphocyte maturation factor 40 kDa subunit|interleukin 12, p40|interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)|interleukin-12 beta chain|interleukin-12 subunit beta|natural killer cell stimulatory factor, 40 kD subunit
|
| Swissprots |
P29460
|
| Accessions |
AAG32620 AAM34792 AJQ18452 CCA63965 EAW61576 P29460 AF180563 AAD56386 AY046592 AAL05890 AY046593 AAL05891 BC067498 AAH67498 BC067499 AAH67499 BC067500 AAH67500 BC067501 AAH67501 BC067502 AAH67502 BC074723 AAH74723 EF173865 ABM53138 HQ447568 ADQ32054 M65272 AAA35695 M65290 AAA59938 NM_002187 NP_002178
|
| Function |
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. {ECO:0000269|PubMed:11114383}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Legionellosis, Proteoglycans in cancer, Herpes simplex infection, Tuberculosis, Inflammatory bowel disease (IBD)
|
