| Gene Symbol |
WBP1
|
| Entrez Gene |
856716
|
| Alt Symbol |
-
|
| Species |
Yeast
|
| Gene Type |
protein-coding
|
| Description |
Wbp1p
|
| Other Description |
-
|
| Swissprots |
P33767 D3DLP5
|
| Accessions |
DAA07649 P33767 NM_001178817 NP_010914
|
| Function |
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
|
| Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis
|