| Gene Symbol | WBP1 |
|---|---|
| Entrez Gene | 856716 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | Wbp1p |
| Other Description | - |
| Swissprots | P33767 D3DLP5 |
| Accessions | DAA07649 P33767 NM_001178817 NP_010914 |
| Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis |