Gene Symbol | ORM1 |
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Entrez Gene | 5004 |
Alt Symbol | AGP-A, AGP1, HEL-S-153w, ORM |
Species | Human |
Gene Type | protein-coding |
Description | orosomucoid 1 |
Other Description | AGP 1|OMD 1|alpha-1-acid glycoprotein 1|epididymis secretory sperm binding protein Li 153w|orosomucoid-1 |
Swissprots | P02763 B7ZKQ5 Q5U067 Q5T539 Q8TC16 |
Accessions | AAB33887 BAA34292 CAA29229 EAW87416 P02763 AK312035 BAG34972 AK316207 BAH14578 BC007032 BC026238 AAH26238 BC104818 AAI04819 BC104820 AAI04821 BC143313 AAI43314 BC143314 AAI43315 BI908589 BT019790 AAV38593 EU794584 ACJ13638 M13692 AAA35515 N68733 X02544 CAA26397 NM_000607 NP_000598 |
Function | Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. {ECO:0000269|PubMed:17008009, ECO:0000269|PubMed:17321687}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
AGP-1 CRISPR/Cas9 KO Plasmid (h) - sc-417102 from Santa Cruz Biotechnology
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AGP-1 HDR Plasmid (h) - sc-417102-HDR from Santa Cruz Biotechnology
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AGP-1 Double Nickase Plasmid (h) - sc-417102-NIC from Santa Cruz Biotechnology
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AGP-1 Double Nickase Plasmid (h2) - sc-417102-NIC-2 from Santa Cruz Biotechnology
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AGP-1 CRISPR Activation Plasmid (h) - sc-417102-ACT from Santa Cruz Biotechnology
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AGP-1 CRISPR Activation Plasmid (h2) - sc-417102-ACT-2 from Santa Cruz Biotechnology
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AGP-1 Lentiviral Activation Particles (h) - sc-417102-LAC from Santa Cruz Biotechnology
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AGP-1 Lentiviral Activation Particles (h2) - sc-417102-LAC-2 from Santa Cruz Biotechnology
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AGP-1/2 siRNA (h) - sc-60133 from Santa Cruz Biotechnology
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AGP-1/2 shRNA Plasmid (h) - sc-60133-SH from Santa Cruz Biotechnology
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AGP-1/2 shRNA (h) Lentiviral Particles - sc-60133-V from Santa Cruz Biotechnology
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alpha 1-Acid Glycoprotein RNAi - H00005004-R01V from Novus Biologicals
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alpha 1-Acid Glycoprotein RNAi - H00005004-R01 from Novus Biologicals
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MISSION® esiRNA - EHU116821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16149 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16149 from Sigma-Aldrich
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ORM1 siRNA (Human) - CRH3322 from Cohesion Biosciences
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shRNA set against Human ORM1 (NM_000607.2) - SHH368504 from Creative biogene
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shRNA set against Human ORM1(NM_000607.2) - SHR081060 from Creative biogene
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Human ORM1 siRNA - orb263824 from Biorbyt
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ORM1 shRNA Plasmid (Human) - CHH3322 from Cohesion Biosciences
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ORM1 miRNA 3'UTR clone - MiUTR1H-07389 from Creative biogene
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