STAM2

Gene Symbol STAM2
Entrez Gene 10254
Alt Symbol Hbp, STAM2A, STAM2B
Species Human
Gene Type protein-coding
Description signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
Other Description HSE1 homolog|Hrs-binding protein|STAM-2|STAM-like protein containing SH3 and ITAM domains 2|signal transducing adapter molecule 2
Swissprots D3DPA1 A8K8A0 Q7LDQ0 Q9UF58 O75886
Accessions AAY14712 EAX11490 EAX11491 EAX11492 O75886 AF042273 AAC63963 AF042274 AAC63964 AK023490 AK292265 BAF84954 AK292847 BAF85536 AK310863 AL133600 CAB63735 AM393419 CAL38297 BC022277 BC028740 AAH28740 BI548350 BQ000599 BU619301 DQ892427 ABM83353 DQ895641 ABM86567 XR_922831 NM_005843 NP_005834
Function Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:12551915}; Peripheral membrane protein {ECO:0000269|PubMed:12551915}; Cytoplasmic side {ECO:0000269|PubMed:12551915}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10899310}.
Top Pathways Jak-STAT signaling pathway, Endocytosis

STAM2 CRISPR/Cas9 KO Plasmid (h) - sc-406277 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 HDR Plasmid (h) - sc-406277-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 Double Nickase Plasmid (h) - sc-406277-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 Double Nickase Plasmid (h2) - sc-406277-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 CRISPR Activation Plasmid (h) - sc-406277-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 CRISPR Activation Plasmid (h2) - sc-406277-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 Lentiviral Activation Particles (h) - sc-406277-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 Lentiviral Activation Particles (h2) - sc-406277-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

STAM2 siRNA (h) - sc-76584 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM2 shRNA Plasmid (h) - sc-76584-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM2 shRNA (h) Lentiviral Particles - sc-76584-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

STAM2 RNAi - H00010254-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU004541 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20693 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20693 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10922 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10922

STAM2 siRNA (Human) - CRH6941 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

STAM2 - MBS8209289 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human STAM2 (NM_005843.4) - SHH419196 from Creative biogene

Category siRNA
Species Reactivities Human

STAM2 shRNA Plasmid (Human) - CHH6941 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

STAM2 miRNA 3'UTR clone - MiUTR4H-TG08588 from Creative biogene

Species Reactivities Human
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