Gene Symbol | EID2 |
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Entrez Gene | 163126 |
Alt Symbol | CRI2, EID-2 |
Species | Human |
Gene Type | protein-coding |
Description | EP300 interacting inhibitor of differentiation 2 |
Other Description | CREBBP/EP300 inhibitor 2|CREBBP/EP300 inhibitory protein 2|E1A like inhibitor of differentiation 2|EID-1-like inhibitor of differentiation 2|EP300-interacting inhibitor of differentiation 2 |
Swissprots | Q6ZR61 Q6X7T0 A7YQ71 Q8N6I1 |
Accessions | EAW56909 Q8N6I1 AK128468 BAC87454 AY251272 AAP12559 BC030137 AAH30137 BC099899 AAH99899 NM_153232 NP_694964 |
Function | Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex. {ECO:0000269|PubMed:12586827, ECO:0000269|PubMed:14585496, ECO:0000269|PubMed:14612439}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14585496}. |
Tissue Specificity | Most abundantly expressed in placenta. Highly expressed in liver, brain, heart, skeletal muscle, and kidney. {ECO:0000269|PubMed:14585496}. |
EID-2 (D-12) - sc-161548 from Santa Cruz Biotechnology
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EID-2 (E-15) - sc-161549 from Santa Cruz Biotechnology
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EID-2 (P-14) - sc-161550 from Santa Cruz Biotechnology
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Anti- EID2 antibody - ab125373 from Abcam
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Anti-EID2 antibody - C-terminal - ab174887 from Abcam
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EID2 Antibody - NBP1-94096 from Novus Biologicals
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ANTI-EID2 (C-TERM) antibody produced in rabbit - SAB1302128 from Sigma-Aldrich
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EID2 Antibody - C-terminal region (OAAB03043) - OAAB03043 from Aviva Systems Biology
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EID2-Antibody-C-term - AP5633b from Abgent, a WuXi AppTec company
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) - 034980 from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (AP) - 034980-AP from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (APC) - 034980-APC from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (Azide free) (HRP) - 034980-HRP from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (Biotin) - 034980-Biotin from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (FITC) - 034980-FITC from USBiological Life Science
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Anti -EID2, CT (EID2, CRI2, EP300-interacting inhibitor of differentiation 2, CREBBP/EP300inhibitor 2, EID-1-like inhibitor of differentiation 2) (PE) - 034980-PE from USBiological Life Science
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EID2 Antibody - abx032575 from Abbexa
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Anti-EID2 (aa 182-216) polyclonal antibody - DPABH-11343 from Creative Diagnostics
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EID2 Polyclonal Antibody - PA5-25543 from Thermo Fisher Scientific
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EID2, Polyclonal Antibody - MBS6011466 from MyBioSource
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EID-2 (C-8) - sc-514902 from Santa Cruz Biotechnology
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EID2, Polyclonal Antibody - MBS9209148 from MyBioSource
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EID2 antibody - orb35924 from Biorbyt
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Anti-EID2 antibody produced in rabbit - HPA045477 from Sigma-Aldrich
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EID2 Antibody - 61-993 from ProSci
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