Gene Symbol |
GSTM4
|
Entrez Gene |
2948
|
Alt Symbol |
GSTM4-4, GTM4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
glutathione S-transferase mu 4
|
Other Description |
GST class-mu 4|GST-Mu2|GTS-Mu2|S-(hydroxyalkyl)glutathione lyase M4|glutathione S-alkyltransferase M4|glutathione S-aralkyltransferase M4|glutathione S-aryltransferase M4|glutathione S-transferase M4|glutathione S-transferase Mu 4
|
Swissprots |
Q05465 Q32NC1 A8K765 Q4JNT8 Q03013 Q6FH87
|
Accessions |
AAA57346 CAA40167 CAA48637 EAW56402 EAW56403 EAW56404 EAW56405 Q03013 AI949679 AK291880 BAF84569 AK311000 BC015513 AAH15513 BC108729 AAI08730 BI458242 BI791533 BM673461 CR541869 CAG46667 DA895954 DQ062813 AAY98515 DQ890658 ABM81584 DQ890659 ABM81585 DQ893839 ABM84765 M96234 AAA57347 M99421 M99422 AAA58623 XM_011541297 XP_011539599 XM_011541298 XP_011539600 NM_000850 NP_000841 NM_147148 NP_671489 NR_024538 NM_147149
|
Function |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Active on 1- chloro-2,4-dinitrobenzene.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Expressed in a wide variety of tissues.
|
Top Pathways |
Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450
|