Gene Symbol | KCNB1 |
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Entrez Gene | 3745 |
Alt Symbol | DRK1, EIEE26, KV2.1, h-DRK1 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated Shab related subfamily B, member 1 |
Other Description | delayed rectifier potassium channel 1|delayed rectifier potassium channel Kv2.1|h-DRK1 K(+) channel|potassium channel protein DRK1|potassium voltage-gated channel subfamily B member 1|potassium voltage-gated channel, Shab-related subfamily, member 1|voltage-gated potassium channel subunit Kv2.1 |
Swissprots | Q14721 Q14193 |
Accessions | CAA48374 EAW75656 Q14721 AF026005 AAB88808 AF086527 AK126976 BC110572 AAI10573 BC110573 AAI10574 BC156166 AAI56167 BC172466 AAI72466 L02840 AAA36156 XM_006723784 XP_006723847 XM_011528799 XP_011527101 NM_004975 NP_004966 |
Function | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | Taste transduction |
KV2.1 CRISPR/Cas9 KO Plasmid (h) - sc-408388 from Santa Cruz Biotechnology
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KV2.1 HDR Plasmid (h) - sc-408388-HDR from Santa Cruz Biotechnology
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KV2.1 Double Nickase Plasmid (h) - sc-408388-NIC from Santa Cruz Biotechnology
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KV2.1 Double Nickase Plasmid (h2) - sc-408388-NIC-2 from Santa Cruz Biotechnology
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KV2.1 CRISPR Activation Plasmid (h) - sc-408388-ACT from Santa Cruz Biotechnology
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KV2.1 CRISPR Activation Plasmid (h2) - sc-408388-ACT-2 from Santa Cruz Biotechnology
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KV2.1 Lentiviral Activation Particles (h) - sc-408388-LAC from Santa Cruz Biotechnology
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KV2.1 Lentiviral Activation Particles (h2) - sc-408388-LAC-2 from Santa Cruz Biotechnology
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KV2.1 siRNA (h) - sc-43885 from Santa Cruz Biotechnology
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KV2.1 shRNA Plasmid (h) - sc-43885-SH from Santa Cruz Biotechnology
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KV2.1 shRNA (h) Lentiviral Particles - sc-43885-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU015191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10925 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10925 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07825 from Sigma-Aldrich
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KCNB1 siRNA (Human) - CRH2521 from Cohesion Biosciences
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KCNB1 RNAi - H00003745-R01 from Novus Biologicals
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KCNB1, siRNA - MBS8202362 from MyBioSource
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shRNA set against Human Kcnb1 (NM_004975.2) - SHH322807 from Creative biogene
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shRNA set against Human KCNB1(NM_004975.2) - SHL188604 from Creative biogene
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Human KCNB1 siRNA - orb263023 from Biorbyt
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KCNB1 shRNA Plasmid (Human) - CHH2521 from Cohesion Biosciences
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KCNB1 miRNA 3'UTR clone - MiUTR1H-05098 from Creative biogene
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