Gene Symbol | MTNR1A |
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Entrez Gene | 4543 |
Alt Symbol | MEL-1A-R, MT1 |
Species | Human |
Gene Type | protein-coding |
Description | melatonin receptor 1A |
Other Description | mel1a receptor|melatonin receptor type 1A |
Swissprots | A0AVC5 P48039 B0M0L2 |
Accessions | BAA85303 EAX04617 P48039 AF435588 AAL30809 BC074946 AAH74946 BC074947 AAH74947 BC113816 AAI13817 BC126297 AAI26298 BC126299 AAI26300 EU432127 ABY87926 HQ258378 ADR83132 U14108 AAB17720 XM_011532002 XP_011530304 NM_005958 NP_005949 |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus. |
Top Pathways | Circadian entrainment, Neuroactive ligand-receptor interaction |
Human Melatonin Receptor 1A protein fragment - ab114688 from Abcam
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MTNR1A / Melatonin Receptor 1a Antibody Blocking Peptide - LS-E22482 from LifeSpan Bioscience
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MTNR1A / Melatonin Receptor 1a Blocking Peptide - LS-E36231 from LifeSpan Bioscience
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MTNR1A / Melatonin Receptor 1a Antibody Blocking Peptide - LS-E27036 from LifeSpan Bioscience
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MTNR1A / Melatonin Receptor 1a Antibody Blocking Peptide - LS-E10044 from LifeSpan Bioscience
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Recombinant Human Melatonin R1A/MT1/MTNR1A Protein - H00004543-Q01 from Novus Biologicals
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Melatonin R1A/MT1/MTNR1A Peptide - NBP1-71113PEP from Novus Biologicals
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MTNR1A-Antibody-Center-Blocking-Peptide - BP9283c from Abgent, a WuXi AppTec company
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Melatonin Receptor 1A blocking peptide - GTX31054-PEP from GeneTex
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MTNR1A Immunizing peptide - orb59538 from Biorbyt
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MTNR1A Blocking Peptide - 33R-3407 from Fitzgerald
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Human Melatonin Receptor 1A Protein - abx067988 from Abbexa
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Melatonin Receptor 1a Blocking Peptide - abx161159 from Abbexa
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Melatonin Receptor 1A Peptide - AC21-1859-P from Abcore
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MTNR1A - H00004543-Q01-10 from Acris Antibodies
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MTNR1A - H00004543-Q01-25 from Acris Antibodies
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MTNR1A Control Peptide - SP4389CP from Acris Antibodies
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Melatonin Receptor 1A (MTNR1A), Human - 20-8617 from ARP American Research Products
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MTNR1A Peptide - 46-987P from ProSci
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MTNR1A fusion protein - Ag24198 from Proteintech Group
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MTR-1A Peptide - 350570 from ABBIOTEC
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Recombinant Human MTNR1A - MTNR1A-30196TH from Creative Biomart
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Recombinant Melatonin Receptor 1A (MTNR1A) - RPC945Hu01 from Uscn Life Science Inc.
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Recombinant Melatonin Receptor 1A (MTNR1A) - RPC945Mu01 from Uscn Life Science Inc.
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ChemiSCREEN™ Membrane Preparation Recombinant Human MT 1 Melatonin Receptor - HTS065M from EMD Millipore
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