KLHL42

Gene Symbol	KLHL42
Entrez Gene	57542
Alt Symbol	Ctb9, KLHDC5
Species	Human
Gene Type	protein-coding
Description	kelch-like family member 42
Other Description	cullin-3-binding protein 9|kelch domain containing 5|kelch domain-containing protein 5|kelch-like family, member 42|kelch-like protein 42
Swissprots	Q9P2K6 Q8N334 Q2VPK1
Accessions	EAW96570 EAW96571 Q9P2K6 AA687307 AB037761 BAA92578 AK002197 AK095405 BAG53048 AL118635 AL702640 BC028742 AAH28742 BC108669 AAI08670 BC137116 AAI37117 BC137117 AAI37118 BQ218827 BX497104 CA771366 CD521625 EU446834 ABZ92363 T83155 XM_011520791 XP_011519093 XR_931314 XR_931315 NM_020782 NP_065833
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis. {ECO:0000269|PubMed:19261606}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:19261606}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:19261606}. Note=Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KLHL42 / KLHDC5 Antibody Blocking Peptide - LS-E18524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL42 / KLHDC5 Antibody Blocking Peptide - LS-E18523 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHDC5 Protein Lysate (APL10738) - APL10738 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

KLHDC5 Protein Lysate (APL10739) - APL10739 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

KLHDC5 Protein Lysate (APL10740) - APL10740 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

KLHDC5 Blocking Peptide - 33R-5301 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KLHDC5 Blocking Peptide - 33R-4199 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KLHDC5 fusion protein - ag20448 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Kelch domain-containing protein 5(KLHDC5) - CSB-YP885803HU CSB-EP885803HU CSB-BP885803HU CSB-MP885803HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KLHDC5 - TP311065 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

KLHDC5 Recombinant Protein Antigen - NBP1-90612PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KLHDC5 Protein Lysate - orb333504 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

KLHDC5 Peptide, Human - M34GP08263H from Creative Peptides Category Peptide Source Synthetic. Species Human

KLHDC5 Protein Lysate - orb333503 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

KLHDC5 Protein Lysate - orb333502 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

Kelch domain-containing protein 5 (KLHDC5), Recombinant Protein - MBS1387567 from MyBioSource Category Protein Prices $1,290.00, $1,290.00, $1,510.00, $1,510.00, $2,125.00, $2,125.00, $2,590.00, $2,590.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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