| Gene Symbol |
wbp1
|
| Entrez Gene |
2539520
|
| Alt Symbol |
-
|
| Species |
S. pombe
|
| Gene Type |
protein-coding
|
| Description |
dolichyl-di-phosphooligosaccharide-protein glycotransferase subunit Wbp1 (predicted)
|
| Other Description |
-
|
| Swissprots |
Q7LWC1 O59866
|
| Accessions |
CAA19346 O59866 NM_001023142 NP_588153
|
| Function |
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000250|UniProtKB:P33767}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P33767}.
|
| Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis
|